Protein Info for BACOVA_04856 in Bacteroides ovatus ATCC 8483

Annotation: putative NADH dehydrogenase subunit K

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 102 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 30 to 49 (20 residues), see Phobius details amino acids 61 to 86 (26 residues), see Phobius details PF00420: Oxidored_q2" amino acids 7 to 102 (96 residues), 83.9 bits, see alignment E=2.8e-28

Best Hits

Swiss-Prot: 47% identical to NUOK_GEOTN: NADH-quinone oxidoreductase subunit K (nuoK) from Geobacillus thermodenitrificans (strain NG80-2)

KEGG orthology group: K00340, NADH dehydrogenase I subunit K [EC: 1.6.5.3] (inferred from 97% identity to bth:BT_4061)

MetaCyc: 39% identical to ferredoxin-plastoquinone oxidoreductase subunit E (Synechococcus elongatus PCC 7942 = FACHB-805)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (102 amino acids)

>BACOVA_04856 putative NADH dehydrogenase subunit K (Bacteroides ovatus ATCC 8483)
MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDINFAVFNRFLFPEGMEG
YFFALFSIAISAAETAVAIAIMINIYRNLRSIQVRNLDELKW