Protein Info for BACOVA_04465 in Bacteroides ovatus ATCC 8483

Annotation: ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1337 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 768 to 793 (26 residues), see Phobius details PF07494: Reg_prop" amino acids 28 to 50 (23 residues), 16.2 bits, see alignment (E = 3.7e-06) amino acids 345 to 368 (24 residues), 21.5 bits, see alignment (E = 7e-08) amino acids 523 to 543 (21 residues), 17.1 bits, see alignment (E = 2e-06) PF07495: Y_Y_Y" amino acids 700 to 764 (65 residues), 61.8 bits, see alignment 1.8e-20 PF00512: HisKA" amino acids 808 to 868 (61 residues), 29.7 bits, see alignment 2.1e-10 PF02518: HATPase_c" amino acids 917 to 1027 (111 residues), 80.6 bits, see alignment E=4.6e-26 PF00072: Response_reg" amino acids 1073 to 1183 (111 residues), 82.3 bits, see alignment E=1.2e-26 PF12833: HTH_18" amino acids 1245 to 1323 (79 residues), 71.5 bits, see alignment 2.4e-23 PF00165: HTH_AraC" amino acids 1290 to 1321 (32 residues), 32.1 bits, see alignment (E = 3.9e-11)

Best Hits

KEGG orthology group: None (inferred from 80% identity to bth:BT_1734)

Predicted SEED Role

"DNA-binding response regulator, AraC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1337 amino acids)

>BACOVA_04465 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (Bacteroides ovatus ATCC 8483)
MKKWLFLILLFPLICVAQTYRYLGVEDGLSNRRVYCIQKDKTGYMWFLTHEGIDRYNGKE
FKRYKLMDGDAEVNSLLNLNWLYIDQEGVLWEIGKKGKVFRYDQIHDCFSLVYKLPMESF
SEQPDPVTYAWLDQNKHIWLCNKDTIFLYNTDTKQVTHIKNDISEEITDIEQIDESHFFI
GTEMGIHYAQLENNALKLINCDKLESVKAQVSDLHFDKKIRKLFIGTFLRGIMVYDMNTK
SVIRPDYNLKDISITRFKPLNDKELLIATDGGGVHKINMDTYQIVPEIVADYNSNCGMNG
NSINDIFVDDEERIWLANYPIGITIQNNRYTSYKWIKHSIGNKQSLINDQVNAIIEDREG
DLWFATNNGISFFNSKTGQWRSVLSAFEESQGNKSHIFLTICEVAPGIIWAGGYSSGAYQ
IDKKTFSVSYFMPPLYTHTNKRPDKYIRDIRTDMQGYIWSGGFYNLKRINLKTQEVRFYD
GLNSITAIVEKDEKSMWIGSATGLCLLDKESGKFERIKLPVESNYIYSLYQAKNGSLYIG
TSGSGLLIYDINKKLFTHYHTENCALISNNIYTILSDADKDIIMSTESGLTSFYPNEKKF
YNWTKDMGLMTTHFNALSGTLRKNNKFILGSSDGAVEFDKDMKLPRSYSSKMIFSDFKLF
YQTIYPGDEDSPLKASINDTKVLKLKYNQNRFSLQVSSINYDYPSNILYSWRLEGFYDKW
SKPGTENTIRYTNLAPGKYTLRVRAISNEDKRIMLEERSMDIIIAQPFWLTFWAMLVYTA
ILCLIAIVLLRILILRKQRKVSDEKIHFFINTAHDIRTPLTLIKAPLEELREKEELSKEG
ISNMNTALRNVNALLRLTTNLINFERADVYSSELYISEHELNTFMNEIFNAFQQYANIKH
INFTYESNFRYMNVWFDKEKMESIFKNIISNALKYTPENGNVQVFVSETSDSWSVEVRDT
GIGIPANEQKKLFKLHFRGSNAINSKVTGSGIGLMLVWKLVRLHKGKINLSSIENQGSVI
KITFPKDSKRFRKAHLATPSKQRIENTIDNVPPPSPEIYENAQKKENINHRRILIVEDND
ELRNYLSQTLSEEYFVQVCSNGKEALTIIPEYKPELVISDIMMPEMRGGDELCQAIKNNI
ETSHIPVILLTALNNEKDILSGLQIGADEYVVKPFNIGILKANVANLLANRALLRSKFAN
LDLNDEENDEDCINCSQDIDWKFIANVKKNVEDNIDNPALTVDVLCSLMGMSRTSFYNKL
RALTDQAPGDYIRLIRLKRAVQLLKEDTHSITEIAEMTGFSDAKYFREVFKKHYNVSPSQ
YGKEKKAVSKEGGEKKE