Protein Info for BACOVA_04210 in Bacteroides ovatus ATCC 8483

Annotation: histidinol phosphate phosphatase HisJ family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02811: PHP
  • amino acids 1 to 189 (189 residues), 49.6 bits, E=3e-17
• TIGR01856: histidinol phosphate phosphatase, HisJ family
  • amino acids 1 to 228 (228 residues), 98.5 bits, E=2.6e-32

Best Hits

KEGG orthology group: K04486, histidinol-phosphatase (PHP family) [EC: 3.1.3.15] (inferred from 85% identity to bth:BT_1478)

Predicted SEED Role

"Histidinol-phosphatase (EC 3.1.3.15)" in subsystem Histidine Biosynthesis (EC 3.1.3.15)

MetaCyc Pathways

• superpathway of histidine, purine, and pyrimidine biosynthesis (42/46 steps found)
• L-histidine biosynthesis (10/10 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Histidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.15

Use Curated BLAST to search for 3.1.3.15

Protein Sequence (260 amino acids)

>BACOVA_04210 histidinol phosphate phosphatase HisJ family (Bacteroides ovatus ATCC 8483)
MDDFIRFAISEGFTSYGISSHAPLPFSTAWTMEWDRMEDYLSEFSRLKKKYAGKIELAIG
LEIDYLNEENNPSLPCFQKLPLDYRIGSVHMLYSPEGKIVDIDTPADLFRQLVDRHFDGD
LDSVVHLYYKNLLRMVELGGFDIVGHADKMHYNASCYRPGLLDEAWYDTLVRDYFAVIAA
RGYMVEINTKSYHELGTFYPNERYFPFLKELGIRVQVNSDAHYPERINNARFEGLAALKK
AGFTSVVEWHGGKWEDIPIG