Protein Info for BACOVA_04171 in Bacteroides ovatus ATCC 8483

Annotation: putative type I restriction-modification system, M subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 510 PF12161: HsdM_N" amino acids 20 to 155 (136 residues), 65.1 bits, see alignment E=1.2e-21 PF02384: N6_Mtase" amino acids 169 to 478 (310 residues), 296.1 bits, see alignment E=3.3e-92

Best Hits

KEGG orthology group: K03427, type I restriction enzyme M protein [EC: 2.1.1.72] (inferred from 52% identity to mmh:Mmah_1043)

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (510 amino acids)

>BACOVA_04171 putative type I restriction-modification system, M subunit (Bacteroides ovatus ATCC 8483)
MAEKVKQYRLPDDPITLDELKSFLWAAATHLRGQIDAAGYKEYIFPLLFFKRISDVYDEQ
FEGFVCEGGVEYAGMQVEDLPIRIPDGAHWRDVREVTENVGNKLVEAFIAIEQANPAKEM
DGRKIGGLEGIFGPKDGWTNKAKMPDNIITSLIEDFSKYTLSLKACPADEMGQAYEYLVG
KFADDAGNTAQEFYTNRTVVQLMAEILQPQPNESIYDPTCGSGGMLVKCLDYLRNKGAEW
QSVQVFGQEVNGLTSSIARMNLYLNGVEDFSIACADTLEHPAFLDGSHLRKFDIVLANPP
YSIKEWNREKFMNDKWGRNFLGTPPQGRADYAFFQHIIASMDRNTGRCAILFPHGVLFRD
EEYELRKKLVEIDIVDCVIGLGPNLFFNASMEACIIICKNRKEDSHKGKVIFIDAKGEVS
RKNAESYLENTHIQKIISAYENFEDIEYFAKVADINDIDNNKSLLSIQSYVKQKGTNEIY
ILDESLPKWIEASRSMHIEVANLLSMLKYE