Protein Info for BACOVA_04086 in Bacteroides ovatus ATCC 8483

Annotation: response regulator receiver domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 PF00072: Response_reg" amino acids 12 to 123 (112 residues), 102.8 bits, see alignment E=1.2e-33 PF02518: HATPase_c" amino acids 265 to 374 (110 residues), 83.1 bits, see alignment E=2e-27

Best Hits

KEGG orthology group: K11527, two-component system, unclassified family, sensor histidine kinase and response regulator [EC: 2.7.13.3] (inferred from 92% identity to bth:BT_1058)

Predicted SEED Role

"Two-component system sensor histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (377 amino acids)

>BACOVA_04086 response regulator receiver domain protein (Bacteroides ovatus ATCC 8483)
MNMEINPSEYKVLIVDDVISNVLLLKVLLTNEKFKIVTAGNGTQALEQVKKENPDLVLLD
VMMPDISGFEVAQQMKADPEMAEIPIIFLTALNSTADIVKGFQVGGNDFISKPFNKEELI
IRVTHQISLVAAKRIIVAQTEELRKTIMGRDKLYSVIAHDLRSPMGSIKMVLNMLILNLP
SETIGDEMYELLTMANQTTEDVFSLLDNLLKWTKSQIGKLKVVYQDINMVEVVEGVSEIF
TMVASLKNIKIVQDVPVENVAVRADIDMIKTVIRNLISNAIKFSNEGSEVVVSLAEEDGM
AIVSVKDSGCGIDDENQKKLLHTDTHFSTFGTNNEEGSGLGLLLCQDFVVKNGGKLWFTS
KKGDGSTFSFSIPLLEK