Protein Info for BACOVA_03646 in Bacteroides ovatus ATCC 8483

Annotation: ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1368 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 792 to 812 (21 residues), see Phobius details PF07494: Reg_prop" amino acids 37 to 60 (24 residues), 25.8 bits, see alignment (E = 2.4e-09) amino acids 456 to 476 (21 residues), 17 bits, see alignment (E = 1.8e-06) amino acids 592 to 614 (23 residues), 17.6 bits, see alignment (E = 1.2e-06) PF07495: Y_Y_Y" amino acids 724 to 784 (61 residues), 47.2 bits, see alignment (E = 6.1e-16) PF00512: HisKA" amino acids 846 to 911 (66 residues), 42.2 bits, see alignment 2.3e-14 PF02518: HATPase_c" amino acids 958 to 1070 (113 residues), 75.8 bits, see alignment E=1.3e-24 PF00072: Response_reg" amino acids 1117 to 1226 (110 residues), 84.9 bits, see alignment E=1.6e-27 PF12833: HTH_18" amino acids 1281 to 1358 (78 residues), 65.7 bits, see alignment 1.3e-21

Best Hits

KEGG orthology group: None (inferred from 71% identity to bth:BT_3800)

Predicted SEED Role

"DNA-binding response regulator, AraC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1368 amino acids)

>BACOVA_03646 ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (Bacteroides ovatus ATCC 8483)
MRSLNLIIIILFISSYPLTSAYAFFDKDIHLLTMQDGLVDNTVTCIYKDEDGFMWFGTNN
GLSRYDGKAIKNFSPLETSIPVEEIVKLSGDYLGIVAGSRLYCFNRKQECFIPAVLEQKT
EGVSALRLLPVDDTSFWAISGDKLQLYQWEEHALQSEYPGSLHIKLQKEFKLLSEKGESF
SAICSDEGGGLCLATNSGYLLLFHPDNPQSYSKVLLEAEKPVRVTSILCKDEIVWISTIS
RGIIRYHKQNRRIDRLSYDATAKENQLSHTDVYQVIPIDNNRYLAVTWSGYTLLMPDKEH
PQKLTTEIYNNTASQVQQNLETRMISAYYDPNGVLWIGTNGGGVMCSDLRSQFYSRFYQD
RHNEICSITMDNDCFVWLATYHKGIMRSMEPYETGKRLQFSTVYSAAGDADETVLCSLKD
AKGNLWFGNKNGELVAYDVKSRQFSVYTLIIDGNVSTSWVWALYMDAHGFLWIGTEQGLL
LFEPKKGVCRRLPVEQKLNSKEKLVVRAIVQAEDGAIWLGTSNKGVCKVTVSASGDISAK
IGYESKKNVESRSVRSLLVSSDGNLYIGYMDGFAILSPRQDSIRELYTTADGLCSNFIGC
ITEDGKGHIWLGSNSGISRYSRHQHLFYNYYIAGSNRSVLFANNTLFFGNNQSMTYFNPD
DVDAYPVNERVLVTGLEVDNRPVEIGKKINNQIILNEGVSFINKIVLDNDNRDFSLTFNN
LSYSKEQQKYNYRLLPYQENWLISDDGEKASYTNLPEGDYIFEVKNIYPDGQTGAVTALK
IKILPHWSRTTLFRLFILLVVIGTVAYLVRLVRVRQRRLEREMQMKHELLTVNLEREKER
QMRMERENFFTGVAHELRTPLTLILAPLQELMKQCNPLETFYKKLQVMYKNASSLHTLID
HLLYVQKIEAGMVKLQLSEADLVEVIKSVSEPFRQMAEIRGLRFEVSLPERKLLYWIDRV
KIVSAIQNLLSNSFKYTSPGGSILLSVSHTRKDGQGYCQIAVSDTGIGIPVDLQKHVFES
FITGENVPEMSTKIGIGLHIVKNTMDLHHGLVTLESMPGEGSTFVLYIPDGKEHFAKDAY
EMVDCQQEYTAQNNEPEPFPLKPENSTQETAAKKSLLIVEDNEDVREYIRSLFISKYTVY
EAGNGEEGVRMAKEKLPDLIISDVMMPVKDGFTCCREIRTQQETAHIPFLMLTAKAEDVD
VLQGSRSGADDYMMKPFNPEILKAKVDNLILQREQLKRIYTKALMLKQKSEEGEQEDAFL
LQLIHAIETNIPNENFNVKMLADQLNMSQPTLYRKVKQRSDLSVIDMIRSIRISKAASLI
LENRYSIQEITEMVGYSDSRTLRKHFTEHFGVSPSKYMGPPTRFPFSS