Protein Info for BACOVA_03629 in Bacteroides ovatus ATCC 8483

Annotation: putative alpha-1,2-mannosidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 760 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR01180: putative alpha-1,2-mannosidase" amino acids 21 to 744 (724 residues), 758.3 bits, see alignment E=3.8e-232 PF17678: Glyco_hydro_92N" amino acids 32 to 259 (228 residues), 223.7 bits, see alignment E=3.1e-70 PF07971: Glyco_hydro_92" amino acids 265 to 739 (475 residues), 559.2 bits, see alignment E=8.7e-172

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2629)

MetaCyc: 100% identical to mannan alpha-1,3-mannosidase (Bacteroides thetaiotaomicron)
3.2.1.-

Predicted SEED Role

"Alpha-1,2-mannosidase" in subsystem Mannose Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (760 amino acids)

>BACOVA_03629 putative alpha-1,2-mannosidase (Bacteroides ovatus ATCC 8483)
MKTHFSFKHLLFLGGAVLYSLQSSAVKNPVDYVSTLVGTQSKFELSTGNTYPATALPWGM
NFWTPQTGKMGDGWAYTYDADKIRGFKQTHQPSPWMNDYGQFAIMPITGGLVFDQDRRAS
WFSHKAEVAKPYYYKVYLADHDVTTELAPTERAVMFRFTYPETKNAYVIVDAFDKGSYVK
VIPEENKIIGYSTKNSGGVPENFKNYFVIQFDKPFTFVSTVFENNILPNETEAKGNHTGA
VIGFATKKGEIVHARVASSFISPEQAELNLKELGKNSFDQLVANGREIWNREMSKIEIED
DNIDNLRTFYSCLYRSMLFPRSFYEIDAKGQVMHYSPYNGEVRPGYMFTDTGFWDTFRCL
FPFLNLMYPSMNQKMQEGLVNTYKESGFLPEWASPGHRDCMVGNNSASVVADAYIKGLRG
YDIETLWEALKHGANAHLRGTASGRLGYESYNQLGYVANNIGIGQNVARTLEYAYNDWAI
YTLGKKLGKPESEIDIYKKHALNYKNVYHPERKLMVGKDNKGVFNPNFDAVDWSGEFCEG
NSWHWSFCVFHDPQGLINLMGGKKEFNAMMDSVFVIPGKLGMESRGMIHEMREMQVMNMG
QYAHGNQPIQHMVYLYNYSSEPWKAQYWIREIMNKLYTAGPDGYCGDEDNGQTSAWYVFS
ALGFYPVCPGTDEYIIGTPLFKSAKLHLENGKTITIKADNNQLDNRYIKEMKVNGKSQTR
NFLTHDQLIKGANIQFQMSPVPNKQRGTTEKDVPYSLSFE