Protein Info for BACOVA_03188 in Bacteroides ovatus ATCC 8483

Annotation: Tat pathway signal sequence domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF01408: GFO_IDH_MocA" amino acids 42 to 159 (118 residues), 54.2 bits, see alignment E=2.3e-18 PF19051: GFO_IDH_MocA_C2" amino acids 204 to 255 (52 residues), 40 bits, see alignment 3.3e-14

Best Hits

KEGG orthology group: None (inferred from 90% identity to bth:BT_2158)

MetaCyc: 90% identical to disaccharide 3-dehydrogenase BT2158 (Bacteroides thetaiotaomicron)
Glucoside 3-dehydrogenase. [EC: 1.1.99.13]; 1.1.99.13 [EC: 1.1.99.13]; 1.1.99.13 [EC: 1.1.99.13]; 1.1.99.13 [EC: 1.1.99.13]

Predicted SEED Role

"Myo-inositol 2-dehydrogenase (EC 1.1.1.18)" in subsystem Inositol catabolism (EC 1.1.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.18

Use Curated BLAST to search for 1.1.1.18 or 1.1.99.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>BACOVA_03188 Tat pathway signal sequence domain protein (Bacteroides ovatus ATCC 8483)
MSNISRRKFLKTGAAALAGITIAPSTILGMSHGHVSPTDKLNLAAVGIGGMGHANINHVK
GTENIVALCDVDWKYAKGVFDEFPKAKKYWDYRKMYDEMGKSIDGVIVATADHTHAIITA
DAMTMGKHVYCQKPLTHSVYESRLLTKLAASTGVVTQMGNQGSSDEGTDLVCEWIWNGEI
GDITKVECATDRPIWPQGLNVPEKVDKIPSTLNWDLFTGPAKMNPYNAIYHPWNWRGWWD
YGTGALGDMACHILHQPFRALKLQYPTKVEGSSTLLLNACAPQAQHVKMIFPARENMPKV
AMPEVEVHWYDGGMMPERPKGFPEGKQLMQSGGGLTIFHGTKDTLICGCYGQNPWLLSGR
KPNAPKVCRRVPNAMNGGHEMDWVRACKENKSNRIMTKSDFSEAGPMNEMVAMGVLAIRL
QALNKTLEWDGANMCFTNIGDNETIRTVIKDGFKIHDGHPTFDKTWTDPINAKQFAAELV
KHTYRDGWRLPDMPR