Protein Info for BACOVA_03187 in Bacteroides ovatus ATCC 8483

Annotation: oxidoreductase, NAD-binding domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 370 PF01408: GFO_IDH_MocA" amino acids 11 to 129 (119 residues), 63.1 bits, see alignment E=4.1e-21 PF02894: GFO_IDH_MocA_C" amino acids 142 to 261 (120 residues), 28.2 bits, see alignment E=1.6e-10

Best Hits

KEGG orthology group: None (inferred from 86% identity to bth:BT_2159)

MetaCyc: 86% identical to disaccharide 3-dehydrogenase BT2159 (Bacteroides thetaiotaomicron)
Glucoside 3-dehydrogenase. [EC: 1.1.99.13]; 1.1.99.13 [EC: 1.1.99.13]; 1.1.99.13 [EC: 1.1.99.13]; 1.1.99.13 [EC: 1.1.99.13]

Predicted SEED Role

"Myo-inositol 2-dehydrogenase (EC 1.1.1.18)" in subsystem Inositol catabolism (EC 1.1.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.18

Use Curated BLAST to search for 1.1.1.18 or 1.1.99.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (370 amino acids)

>BACOVA_03187 oxidoreductase, NAD-binding domain protein (Bacteroides ovatus ATCC 8483)
MNTQSSVDTRIKVGIIGFGRMGRFYWEAMTKSDRWNIAYICDTDPASRQLAKKLSPNSII
VEDNQKIFEDESVQVVGLFTLADSRMEQIEKAIRYGKHIISEKPVADTMENEWKVVEMTE
NTNLISTVNLYLRNSWYHNLMKEYIQQGEIGELAIIRICHMTPGLAPGEGHEYEGPAFHD
CGMHYVDITRWYAGCDYRTWNAQGVNMWNYKDPWWVQCHGTFQNGVVFDITQGFVYGQLS
KDQTHNSYVDIIGTKGVVRMTHDFNTAVVDLHGVNQTIRVEKPFGGKNIDVLCDLFADSV
ETGKRSSRLPLMRDSAIASEYAWTFLKDTRKHDLPAIGNLRTLEQIRERRKNMKNGYGLL
HGNLPKIINP