Protein Info for BACOVA_02399 in Bacteroides ovatus ATCC 8483

Annotation: MATE efflux family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 21 to 38 (18 residues), see Phobius details amino acids 50 to 75 (26 residues), see Phobius details amino acids 95 to 118 (24 residues), see Phobius details amino acids 138 to 157 (20 residues), see Phobius details amino acids 169 to 190 (22 residues), see Phobius details amino acids 196 to 217 (22 residues), see Phobius details amino acids 238 to 261 (24 residues), see Phobius details amino acids 275 to 298 (24 residues), see Phobius details amino acids 318 to 340 (23 residues), see Phobius details amino acids 360 to 381 (22 residues), see Phobius details amino acids 391 to 412 (22 residues), see Phobius details amino acids 419 to 441 (23 residues), see Phobius details PF01554: MatE" amino acids 24 to 185 (162 residues), 92.5 bits, see alignment E=2.4e-30 amino acids 250 to 403 (154 residues), 80.4 bits, see alignment E=1.2e-26 TIGR00797: MATE efflux family protein" amino acids 24 to 419 (396 residues), 216.3 bits, see alignment E=3.4e-68 PF14667: Polysacc_synt_C" amino acids 139 to 275 (137 residues), 37.5 bits, see alignment E=2.6e-13

Best Hits

KEGG orthology group: None (inferred from 93% identity to bth:BT_0696)

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>BACOVA_02399 MATE efflux family protein (Bacteroides ovatus ATCC 8483)
MSKNDPHILGKESIGKLLLQYSIPAIIGMTITSIYNIIDSIFIGHGVGPMAIAGLAISFP
LMNLVVAFCTLVSAGGSTLASIRLGQKDMKGATEILSHTLMLCITNSFFFGILSFIFLDD
ILVFFGASSETLPYARSFMQVILLGTPITYTMIGLNNVMRATGYPKKAMLTSMVTVVANI
ILAPIFIFHFEWGMRGAATATVISQLIGMVWVVSHFVKKDSTVHFEGNIWKMKRRIVESI
FAIGMSPFLMNVCACAIVIIINNSLQNYGGDMAIGAYGIINRLLTLYVMIVLGLTMGMQP
IVGYNFGAQKIDRVKQTLRLGIISGVVITSSGFIICEFFPHAVSALFTDSDELIDLAVDG
IRLAVLMFPFVGAQIVIGNFFQSIGKAKISIFLSLTRQLLYLLPCLLLFPNWWGLEGIWI
SMPVSDALAFITAVVSLMIYIKKVSKQHPETVAE