Protein Info for BACOVA_02381 in Bacteroides ovatus ATCC 8483

Annotation: outer membrane efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF02321: OEP" amino acids 29 to 212 (184 residues), 93 bits, see alignment E=1.1e-30 amino acids 242 to 415 (174 residues), 89.9 bits, see alignment E=9.7e-30

Best Hits

KEGG orthology group: None (inferred from 86% identity to bth:BT_0678)

Predicted SEED Role

"Heavy metal RND efflux outer membrane protein, CzcC family" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>BACOVA_02381 outer membrane efflux protein (Bacteroides ovatus ATCC 8483)
MNRVFLISFFLLLTGGICAQQATTGTLTLKEAEQRFLERNLSLIAERYNIDMAQAQVLQA
KLFENPVISLEQNVYNRLNGKYFDFGKEGEMVVGIEQVIRLAGQRNKQVKLEKINKEIAE
YQFEEVMRTLRQELNEKFVQVYFLSKSISIYEKEVNSLQELLAGMKLQQEKGNISLMEMS
RLESMLFSLKKEKNERENELLTLRGELNVLLNLPGDTMVELSLDEEVLKQLDLSQLSFAD
LKAMVNERPDLKIARSTVSASRANLKLQKSMAFPEFSVNGSYDRAGNFINNYFAIGVSLS
VPIFNRNQGNVKAARFSIQQAGAEQENAANRADMELYTAYASLDKAVQLYQSTNMELERN
FEKLIAGVNENFKKRNISLLEFIDYYDSYKETCIQLHEIKKDVFLAMENLNTTIGQTILN
Y