Protein Info for BACOVA_01619 in Bacteroides ovatus ATCC 8483

Annotation: acetyl xylan esterase (AXE1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF05448: AXE1" amino acids 133 to 426 (294 residues), 171.5 bits, see alignment E=1.9e-54 PF00326: Peptidase_S9" amino acids 285 to 409 (125 residues), 29.8 bits, see alignment E=4.2e-11

Best Hits

Swiss-Prot: 66% identical to AXE7A_PRER2: Acetyl esterase Axe7A (axe7A) from Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23)

KEGG orthology group: None (inferred from 83% identity to bth:BT_2525)

Predicted SEED Role

"Acetyl xylan esterase 1; Cephalosporin-C deacetylase (EC 3.1.1.41)" (EC 3.1.1.41)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.41

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>BACOVA_01619 acetyl xylan esterase (AXE1) (Bacteroides ovatus ATCC 8483)
MNNTMKRLLLSVWLLSLSLLSAVAENYPYKSDVLWVTVPNHADWLYKTGEKVTVEVQFYK
YGIPRDNVTVTYEIGGDMMPVADTKGSITLKNGRGVIPVGTMKEPGFRDCRLKATVDGKT
YSHHIKVGFSPEKLRPYTTMPSDFKEFWEKAKAEQKEFPLTYTKEHVEKYSTDKIDCYLV
KLQLNKRRQCVYGYLFYPKKEGKFPVVLCPPGAGIKTIKEPLRHKYYAEQGCIRFEFEIH
GLNPEMTDEEFKEISNAFNGRENGYLTNGLDSRDNYYMKRVYLACVRGIDFLTSLPEWDG
KNVIAQGGSQGGALALIAAGLDERVTACVANHPALSDMAGYKAGRAGGYPHFFRNSVDMD
TPEKIKTMAYYDVVNFAKLIKVDTYMTWGFNDDVCPPTTSYIVYNVLNCPKEALITPINE
HWTSNDTEYGHLLWIKKHLK