Protein Info for BACOVA_01422 in Bacteroides ovatus ATCC 8483

Annotation: anaerobic ribonucleoside-triphosphate reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 797 PF03477: ATP-cone" amino acids 7 to 91 (85 residues), 79.8 bits, see alignment E=2.7e-26 PF13597: NRDD" amino acids 119 to 796 (678 residues), 673.7 bits, see alignment E=3.7e-206 TIGR02487: anaerobic ribonucleoside-triphosphate reductase" amino acids 415 to 796 (382 residues), 423.8 bits, see alignment E=5.4e-131 PF01228: Gly_radical" amino acids 681 to 751 (71 residues), 23.2 bits, see alignment E=1.2e-08

Best Hits

KEGG orthology group: K00527, ribonucleoside-triphosphate reductase [EC: 1.17.4.2] (inferred from 94% identity to bth:BT_1998)

Predicted SEED Role

"Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)" in subsystem Ribonucleotide reduction (EC 1.17.4.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.17.4.2

Use Curated BLAST to search for 1.17.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (797 amino acids)

>BACOVA_01422 anaerobic ribonucleoside-triphosphate reductase (Bacteroides ovatus ATCC 8483)
MNYAEICIIKRDGKREDFSISKIKNAISKAFSATGIQDEQQLVADITMNVISQFTTPTIT
VEEIQDLVEKSLMKVRPEVAKKYIIYREWRNTERDKKTQMKQVMDGIVAIDKNDVNLSNA
NMSSHTPAGQMMTFASEVTKDYTYKYLLPKRFAEAHQLGDIHIHDLDYYPTKTTTCIQYD
MDDLFERGFRTKNGSIRTPQSIQSYATLATIIFQTNQNEQHGGQAIPAFDFFMAKGVAKS
FRKHLASFINFYVAMENGNQADEKSIRTLIKEYLPSIKTTEAERETLRIALVALQIIIDK
EHLARIVEKAYQQTRKDTHQAMEGFIHNLNTMHSRGGNQVVFSSINYGTDTSAEGRMVIE
ELLKATIEGLGTRGEVPVFPIQIFKVKDGVSYSEKDFEKAMKAENIEEAMTDRYEAPNFD
LLLKACQTTAKALFPNFMFLDAPFNQNEKWRADDPKRYIYELATMGCRTRVFENVAGEKS
SLGRGNLSFTTLNMPRLAIEARIKAENLIEDERNKDAIEQKAKEIFIESVHQMSVLVADQ
LYERYQYQRTALARQFPFMMGNNVWKGGGELNPNEQVGDALRSGTLGIGFIGGHNAMVAL
YGQGHGHNQKAWDTLYEAVMEMNKVVNEYKEKYNLNYSVLATPAEGLSGRFTKMDRRKYG
KIPGVTDRDYYVNSFHVDVKEPISIVEKIKREAPFHAITRGGHITYVELDGEAQKNVRAI
AKIVKVMHDEGIGYGSINHPVDTCHNCGYKGVIFDKCPVCQSESILRMRRITGYLTGDLS
SWNSAKRAEEQDRVKHL