Protein Info for BACOVA_01202 in Bacteroides ovatus ATCC 8483

Annotation: methionyl-tRNA formyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 336 TIGR00460: methionyl-tRNA formyltransferase" amino acids 19 to 328 (310 residues), 261.4 bits, see alignment E=5.4e-82 PF00551: Formyl_trans_N" amino acids 20 to 196 (177 residues), 126.9 bits, see alignment E=7.9e-41 PF02911: Formyl_trans_C" amino acids 224 to 327 (104 residues), 80.9 bits, see alignment E=6.5e-27

Best Hits

Swiss-Prot: 90% identical to FMT_BACTN: Methionyl-tRNA formyltransferase (fmt) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K00604, methionyl-tRNA formyltransferase [EC: 2.1.2.9] (inferred from 90% identity to bth:BT_3945)

Predicted SEED Role

"Methionyl-tRNA formyltransferase (EC 2.1.2.9)" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase or Folate Biosynthesis (EC 2.1.2.9)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (336 amino acids)

>BACOVA_01202 methionyl-tRNA formyltransferase (Bacteroides ovatus ATCC 8483)
MQITGCYADYKTIMKKEDLRIVYMGTPDFAVEALRQLVEGGYNVVGVITMPDKPAGRGHK
IQYSPVKQYALEQNLPLLQPERLKDEVFVEALREWKADLQIVVAFRMLPEVVWNMPRLGT
FNLHASLLPQYRGAAPINWAVINGDTETGITTFFLKHEIDTGEVIQQVHVPIADTDNVEV
VHDKLMVLGGKLVLETVDAILNGTVKPIPQEEMAVVGELRPAPKIFKETCRIDWNQPVKK
IYDFIRGLSPYPAAWSELITSEEGAAVVVKIFESEKIYESHQLATGTIVTDGKKFMKVAV
PDGFVSILSLQLPGKKRLKIDELLRGYHLEDGCLMK