Protein Info for BACOVA_00930 in Bacteroides ovatus ATCC 8483

Annotation: homoserine dehydrogenase, NAD binding domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF03447: NAD_binding_3" amino acids 8 to 125 (118 residues), 67.4 bits, see alignment E=1.9e-22 PF01958: Asp_DH_C" amino acids 170 to 242 (73 residues), 49 bits, see alignment E=5.8e-17

Best Hits

KEGG orthology group: K06989, aspartate dehydrogenase [EC: 1.4.1.21] (inferred from 79% identity to bvu:BVU_0071)

Predicted SEED Role

"L-Aspartate dehydrogenase (EC 1.4.1.21) homolog" (EC 1.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (262 amino acids)

>BACOVA_00930 homoserine dehydrogenase, NAD binding domain protein (Bacteroides ovatus ATCC 8483)
MKKLVIVGCGRLAEIVADAVVKGSLPDYDLVGVYSRTASKAAHIVNKMQQHGKPCIACAK
LEELLALKPDYLVESASPAAMRELALPALKNGTSVITLSIGALADEVFYREVTETARANG
TRVYIASGATGGFDVLRTASLMGNTTARFFNEKGPNGLKGTPVYDDSLQTEQRTVFSGSA
AEAIRLFPTKVNVTVAASRASVGPENMQVSIQSTPGFVGDTQRVEIKNDQVHAVVDIYSA
TSDIAGWSVVSTLINIASPIVF