Protein Info for BACOVA_00816 in Bacteroides ovatus ATCC 8483

Annotation: metallo-beta-lactamase domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 PF00753: Lactamase_B" amino acids 23 to 103 (81 residues), 54.6 bits, see alignment E=1.4e-18 PF12706: Lactamase_B_2" amino acids 33 to 92 (60 residues), 31.4 bits, see alignment E=1.4e-11

Best Hits

KEGG orthology group: K06897, (no description) (inferred from 84% identity to bth:BT_1410)

Predicted SEED Role

"7,8 dihydropteroate synthase (methanopterin)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (270 amino acids)

>BACOVA_00816 metallo-beta-lactamase domain protein (Bacteroides ovatus ATCC 8483)
MGYKITTLVENCVYGRKLQAEHGLSLYIETQEHRLLFDTGASDLFIRNARLLHIDLQKVD
YLILSHGHSDHTGGLRYFLELNTQATVVCKREIFSPKFKDERENGMIHTQNLDRSRFRFI
TEQTELLPGVFLFPSIDIINQADTHFERFWVQQEDGCKIPDTFQDELAMVLVEPEGFSVL
SACSHRGITNILRTVQAAFPESPCKLLLGGFHIHNAEKQKYQVIADYLQEYLPRQIGVCH
CTGVDKYAFFYKDFGDSTFYNYTGKLIQTD