Protein Info for BACOVA_00801 in Bacteroides ovatus ATCC 8483

Annotation: anaerobic ribonucleoside-triphosphate reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 transmembrane" amino acids 217 to 237 (21 residues), see Phobius details PF03477: ATP-cone" amino acids 7 to 88 (82 residues), 74.7 bits, see alignment E=6.9e-25 TIGR02827: anaerobic ribonucleoside-triphosphate reductase" amino acids 88 to 693 (606 residues), 955.8 bits, see alignment E=4.8e-292 PF13597: NRDD" amino acids 138 to 691 (554 residues), 315.1 bits, see alignment E=1e-97

Best Hits

KEGG orthology group: K00527, ribonucleoside-triphosphate reductase [EC: 1.17.4.2] (inferred from 93% identity to bvu:BVU_3105)

Predicted SEED Role

"Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)" in subsystem Ribonucleotide reduction (EC 1.17.4.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.17.4.2

Use Curated BLAST to search for 1.17.4.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (697 amino acids)

>BACOVA_00801 anaerobic ribonucleoside-triphosphate reductase (Bacteroides ovatus ATCC 8483)
MISSEIFIIKRDGKKEAFSLDKIKNAISKAFLSVGSFATQDVITNVLSRVSISDGTNVEE
IQNQVEVALMAEHYYSVAKAYMLYRQKHLEDREVRDKLKFLMDYCDASNPASGSKYDANA
NVENKNIATLIGELPKSNFIRLNRRLLTDRLRDMYGKEASDRYLELLNHHFIYKNDETNL
ANYCASITMYPWLIAGTTAVGGNSTAPTNLKSFCGGFINMVFIVSSMLSGACATPEFLMY
MNYFIGLEYGQDYYKHPDKLADLSLKQRSIDKIITDCFEQIVYSINQPTGARNFQAVFWN
VAYYDKYYFNSLFEHFVFPDGSKPDWDSLSWLQKRFMKWFNKERTRTVLTFPVETMALLT
KDGDVLDKEYGDFTAEMYAEGHSFFTYMSDNADSLSSCCRLRNEIQDNGFSYTLGAGGVS
TGSKSVLTINLNRCIQHAVKSGILYPFFLEEVVDLVHKVQLAYNENLKLLQAKGMLPLFD
AGYINMSRQYLTIGVNGLVEAAQFMGIDINDNPKYEAFVQEILGMIEKYNKKYRTKEVLF
NCEMIPAENVGVKHAKWDKEAGFQTYRECYNSYFYIVEDKSLNIVDKFRLHGHRYIEHLT
GGSALHMNLEEHLSKEQYRQLLRVAATEGCNYFTFNIPNTVCNKCHHIDKRYLHECPECH
SENVDYLTRVIGYMKRISNFSQARQKEADLRYYAPVR