Protein Info for BACOVA_00423 in Bacteroides ovatus ATCC 8483

Annotation: efflux transporter, outer membrane factor lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 459 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 12 to 454 (443 residues), 330.1 bits, see alignment E=1.2e-102 PF02321: OEP" amino acids 62 to 244 (183 residues), 74.2 bits, see alignment E=6.1e-25 amino acids 272 to 452 (181 residues), 98.5 bits, see alignment E=2.1e-32

Best Hits

KEGG orthology group: None (inferred from 93% identity to bth:BT_0306)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (459 amino acids)

>BACOVA_00423 efflux transporter, outer membrane factor lipoprotein, NodT family (Bacteroides ovatus ATCC 8483)
MKRKKLYIAILLLAGVLTSCKVGKSYVRPDLHLPDSLERSQDSVSFGDQDWRDIYTDATL
RSLIERALDHNKDMLIAAARVKEMAAQKRISTAALLPDIKGKVTGERELENHGGDAFKRS
DTFEAQFLVSWEVDLWGNLRWARSASIAEYLQSIEAQRALQMTIVAEVAQAYYELVALDT
ELDIVKQTLKAREEGVRLARIRFAGGLTSETSYRQAQVELARTATLVPDLERKISLKEND
IAYLAGEYPNKIARSRLLQEFNSPETLPVGLPSTLLERRPDIRQAEQKLIAANAKVGVAY
TNMFPRLALTGGFGSESTSLSELLKSPYAVMEGALLTPIFGWGKNRAALKAKKAAYEAEV
HSYEKSVLEAFKETRNAIVNFNKIKEVYELRANLERSAKSYMDLAQLQYINGVINYLDVL
DAQRGYFDAQIGLSNAIRDELIAVVQLYKALGGGWEQNP