Protein Info for B158DRAFT_2533 in Kangiella aquimarina DSM 16071

Annotation: Uncharacterized conserved protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02578: Cu-oxidase_4
  • amino acids 20 to 238 (219 residues), 255.5 bits, E=2.2e-80
• TIGR00726: YfiH family protein
  • amino acids 25 to 239 (215 residues), 202.6 bits, E=2.7e-64

Best Hits

Swiss-Prot: 48% identical to POLOX_ECOLI: Polyphenol oxidase (yfiH) from Escherichia coli (strain K12)

KEGG orthology group: K05810, conserved hypothetical protein (inferred from 74% identity to kko:Kkor_1083)

MetaCyc: 48% identical to purine nucleoside phosphorylase YfiH (Escherichia coli K-12 substr. MG1655)
Adenosine deaminase. [EC: 3.5.4.4]; S-methyl-5'-thioadenosine phosphorylase. [EC: 3.5.4.4, 2.4.2.28]; Purine-nucleoside phosphorylase. [EC: 3.5.4.4, 2.4.2.28, 2.4.2.1]; 2.4.2.1 [EC: 3.5.4.4, 2.4.2.28, 2.4.2.1]; Laccase. [EC: 3.5.4.4, 2.4.2.28, 2.4.2.1, 1.10.3.2]

Predicted SEED Role

"COG1496: Uncharacterized conserved protein"

MetaCyc Pathways

• adenine and adenosine salvage III (4/4 steps found)
• superpathway of purine nucleotide salvage (11/14 steps found)
• S-methyl-5'-thioadenosine degradation II (1/1 steps found)
• adenine and adenosine salvage V (2/3 steps found)
• adenine and adenosine salvage I (1/2 steps found)
• guanine and guanosine salvage I (1/2 steps found)
• xanthine and xanthosine salvage (1/2 steps found)
• adenosine nucleotides degradation II (3/5 steps found)
• inosine 5'-phosphate degradation (2/4 steps found)
• superpathway of guanine and guanosine salvage (1/3 steps found)
• purine ribonucleosides degradation (3/6 steps found)
• guanosine nucleotides degradation III (1/4 steps found)
• purine nucleotides degradation II (aerobic) (6/11 steps found)
• ureide biosynthesis (2/7 steps found)
• L-methionine salvage cycle III (4/11 steps found)
• sesamin biosynthesis (1/8 steps found)
• justicidin B biosynthesis (1/10 steps found)
• matairesinol biosynthesis (1/10 steps found)
• nucleoside and nucleotide degradation (archaea) (1/10 steps found)
• salinosporamide A biosynthesis (2/15 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Methionine metabolism
• Nicotinate and nicotinamide metabolism
• Purine metabolism
• Pyrimidine metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.10.3.2 or 2.4.2.1 or 2.4.2.28 or 3.5.4.4

Protein Sequence (241 amino acids)

>B158DRAFT_2533 Uncharacterized conserved protein (Kangiella aquimarina DSM 16071)
MIELIKPSWPAPVNIQAFSTTRVGGVSKAPFDSLNLGLHVGDDEVSVMTNRKRLQQLTTH
PPVQWLNQIHSSNVVEYSGTDQLVEADAIVTSQTSATCAVMTADCLPVLMTNSSGSWVAA
AHAGWRGLADGILLKTVASYDRPEPLMAWIGPAISQKCFEVGDEVKEAFLDLDASNQDYF
VQNNRGRWQADLAGLAKKQLESEGVAVYLSQLCTYENEQQFYSYRRDGGTGRMASMIWIS
E