Protein Info for B158DRAFT_2455 in Kangiella aquimarina DSM 16071

Annotation: Transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 PF00126: HTH_1" amino acids 3 to 63 (61 residues), 51.8 bits, see alignment E=6.2e-18 PF03466: LysR_substrate" amino acids 89 to 292 (204 residues), 135.8 bits, see alignment E=1.4e-43

Best Hits

Swiss-Prot: 45% identical to CYSB_ECOLI: HTH-type transcriptional regulator CysB (cysB) from Escherichia coli (strain K12)

KEGG orthology group: K13634, LysR family transcriptional regulator, cys regulon transcriptional activator (inferred from 87% identity to kko:Kkor_1616)

MetaCyc: 45% identical to DNA-binding transcriptional dual regulator CysB (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"LysR family transcriptional regulator YeiE" in subsystem YeiH

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>B158DRAFT_2455 Transcriptional regulator (Kangiella aquimarina DSM 16071)
MKLQQLKYLIAIADNNLSITSAAQKIFTSQPGISKQLRLLEDELQTKIFERNGKQLVGIT
QVGKEILARARKVMQEINNIKRLSSEISQQDSGCFSIGTTQTQAQYVLPRTFSTFHKEYP
GLKIDLHQGTTEQIIEQLNKQEIDFVIASGNVELGPDIVQIPCYQWDRTLLFPQDHALGD
LRKISLEDLVQYPLVTYNFSDKASSSLLRACKEQKLEPNIVFTARDADIIKTYVRKGFGV
GIIASMAYDNEHDKDLISYSTREMLPKCTTWLAFNKNLFLKQYMKDFIELFAPHISQQEL
IRYLYSEHTSSSELLNRIKANDSKGIEFRRVVSA