Protein Info for B158DRAFT_2413 in Kangiella aquimarina DSM 16071

Annotation: prepilin-type N-terminal cleavage/methylation domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details PF07963: N_methyl" amino acids 5 to 29 (25 residues), 29.5 bits, see alignment (E = 3.9e-11) TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 8 to 29 (22 residues), 22.5 bits, see alignment (E = 3.7e-09) PF16074: PilW" amino acids 135 to 235 (101 residues), 69.1 bits, see alignment E=3.8e-23

Best Hits

Predicted SEED Role

"Type IV fimbrial biogenesis protein PilW" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (242 amino acids)

>B158DRAFT_2413 prepilin-type N-terminal cleavage/methylation domain (Kangiella aquimarina DSM 16071)
MKSINKSNGFTLIEYMVAITIGLILLAGVGTFFLGMQKSSQAQNGISELQENGRFALYFL
TNEIQMAGWKEPDFIIGASTPNYIDLTGTSDGGAANVSDSLQIRYESDVDCLGNAAAGGV
ATNRFFVEDGQLKCGAGGASQPIINGVEVAHFLYGVDTDRDNTPEKYVTASQLAANPVEA
RQVASVKVILLLASDTNVADTNTARTFTILGEGEFTANNDRKLRRIFSSTIFLPNRPKYL
GS