Protein Info for B158DRAFT_2390 in Kangiella aquimarina DSM 16071

Annotation: regulatory inactivation of DnaA Hda protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 TIGR03420: DnaA regulatory inactivator Hda" amino acids 3 to 227 (225 residues), 249.8 bits, see alignment E=1.2e-78 PF00308: Bac_DnaA" amino acids 11 to 206 (196 residues), 67.5 bits, see alignment E=8.2e-23

Best Hits

Swiss-Prot: 44% identical to HDA_PECAS: DnaA regulatory inactivator Hda (hda) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K10763, DnaA-homolog protein (inferred from 86% identity to kko:Kkor_1681)

Predicted SEED Role

"Chromosomal replication initiator protein DnaA" in subsystem DNA-replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (229 amino acids)

>B158DRAFT_2390 regulatory inactivation of DnaA Hda protein (Kangiella aquimarina DSM 16071)
MQQLPLDIELHSDATFANFVEGENQLLLQKLDSICQGDNDFIYIYSEKGHGRSHLLQALT
HAFSEQNPDKLIAYLPLDNRMLHPQMLDGLVAFDCVSLDGVDEVIGQLEWQTAIFNLYNQ
LKEQGKSLLVTGLVAPSQLGIELQDLKSRLSAMFIYNIKPLNDEEKRILLQKKAQERGLE
LGTDVAQYLLARQQRDLPTLLEILDKLDQASLQAKRKLTIPFIKEVLDL