Protein Info for B158DRAFT_2121 in Kangiella aquimarina DSM 16071

Annotation: cell division protein FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 transmembrane" amino acids 28 to 52 (25 residues), see Phobius details amino acids 64 to 83 (20 residues), see Phobius details amino acids 94 to 112 (19 residues), see Phobius details amino acids 131 to 148 (18 residues), see Phobius details amino acids 160 to 177 (18 residues), see Phobius details amino acids 182 to 199 (18 residues), see Phobius details amino acids 205 to 221 (17 residues), see Phobius details amino acids 290 to 310 (21 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details amino acids 359 to 378 (20 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 27 to 383 (357 residues), 434.6 bits, see alignment E=1.4e-134 PF01098: FTSW_RODA_SPOVE" amino acids 34 to 384 (351 residues), 368.1 bits, see alignment E=2.3e-114

Best Hits

Swiss-Prot: 52% identical to FTSW_LEGPH: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 94% identity to kko:Kkor_0688)

MetaCyc: 49% identical to peptidoglycan glycosyltransferase FtsW (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (407 amino acids)

>B158DRAFT_2121 cell division protein FtsW (Kangiella aquimarina DSM 16071)
MTSILNTLRITDFMEQLKLSDPRTRLDPWLLGPVMILLAIGLMMVASSSMPFAEDHMNGN
EFHFLIRHIIYLSIAVVASVLVLQLDTRFWQVNGIYMLLLGIILLMLVLVIGKEVNGSKR
WIGVGPLTVQPAELMKFFIVTYLAGYLVRRSDELQTQIKGFTKPLLVIGLVVAFLLLQPD
FGSSAVIVATALAMLFLAGAKLWQFISLTAFVGVVMALVAWKEPYRMKRLTSFLDPWADQ
FGSGYQLVQSLIAFGRGDWFGVGLGNSVQKLSYLPEAHTDFVFAVFAEEFGFVGVLFVII
LFSIILLRSLSIGRRALKMEQYFAAYISYGFGFWLSLQALINIGVSSGSLPTKGLTLPFI
SYGGNSLIVTCMAIAIILRVDFEVRRREHEFAKVKREYRSARGGQDD