Protein Info for B158DRAFT_2030 in Kangiella aquimarina DSM 16071

Annotation: vacuolar-type H(+)-translocating pyrophosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 667 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 55 to 73 (19 residues), see Phobius details amino acids 79 to 99 (21 residues), see Phobius details amino acids 120 to 149 (30 residues), see Phobius details amino acids 155 to 173 (19 residues), see Phobius details amino acids 230 to 247 (18 residues), see Phobius details amino acids 257 to 278 (22 residues), see Phobius details amino acids 288 to 308 (21 residues), see Phobius details amino acids 318 to 339 (22 residues), see Phobius details amino acids 359 to 384 (26 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details amino acids 454 to 472 (19 residues), see Phobius details amino acids 494 to 521 (28 residues), see Phobius details amino acids 560 to 580 (21 residues), see Phobius details amino acids 586 to 607 (22 residues), see Phobius details amino acids 649 to 666 (18 residues), see Phobius details TIGR01104: V-type H(+)-translocating pyrophosphatase" amino acids 6 to 667 (662 residues), 771.4 bits, see alignment E=5.2e-236 PF03030: H_PPase" amino acids 13 to 663 (651 residues), 845.7 bits, see alignment E=1.4e-258

Best Hits

KEGG orthology group: K01507, inorganic pyrophosphatase [EC: 3.6.1.1] (inferred from 95% identity to kko:Kkor_0597)

Predicted SEED Role

"Pyrophosphate-energized proton pump (EC 3.6.1.1)" in subsystem Phosphate metabolism (EC 3.6.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.1

Use Curated BLAST to search for 3.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (667 amino acids)

>B158DRAFT_2030 vacuolar-type H(+)-translocating pyrophosphatase (Kangiella aquimarina DSM 16071)
MTDNMILPPLLGLIGMAFAFIIYFVVKKYPEGEDKVKKIGDAIHSGAMVFMNREYRMLAM
FAGILLIILWLSPLGGYTALAFAVGAVSSALAGYIGMYTATKANVRTTTAAHTKGAAEAL
SVAFFGGSIMGLCVASLGLIGLGGLYWYFGGDPESAHYIHGFGMGASSVALFSRVGGGIF
TKSADVGADLVGKIEAGIPEDDPRNPGVIADNVGDNVGDVAGMGSDIFESYCGAMIASIA
IAATMSTSDLGAQNVLMATPLALASVGLICSILGIMIVKMMSSNKPEVALRVGTIGAAVL
FVIAAYFLLQNMDVSNNVWFAVLCGAVGGIIIGLVTEYYTSGAPIRHIAKSGETGPATVM
ISGLAVGMQSVVVPVLTLAAIIFISTELAGLYGVGIAAVGMLATVGITMAIDAYGPVADN
AGGIAEMGGLGKETREITDSLDELGNTTAAIGKGFAIGAAALAALAIIAAFVETLNAKHG
ADDFVLHIGDPQVLMGLFIGGLIPFLIASITMTAVGDAAFAMIHEIRRQFKEITGLLEGK
AEPDTEKCVAIATDAALKKMILPGVIAVAAPPLVGFLLGAEALGGMLGGALVSAVLLALM
MANAGGAWDNAKKHVEKGNFGGKGSDVHAATVVGDTVGDPFKDTSGPSMNILINVMAIVS
LVIAPLL