Protein Info for B158DRAFT_1932 in Kangiella aquimarina DSM 16071

Annotation: Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 PF00072: Response_reg" amino acids 6 to 114 (109 residues), 76.3 bits, see alignment E=2.1e-25 PF02954: HTH_8" amino acids 148 to 186 (39 residues), 45.5 bits, see alignment 4.9e-16

Best Hits

KEGG orthology group: K15012, two-component system, response regulator RegA (inferred from 82% identity to kko:Kkor_0497)

Predicted SEED Role

"Dna binding response regulator PrrA (RegA)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>B158DRAFT_1932 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain (Kangiella aquimarina DSM 16071)
MTSHLLLIEDDAVFAQVLQNSLQKRGINCTHVSTLEQASAAELPGDFDAIVLDLYLDGES
GLSILPQLRQRYPKASILVLTGYASIATTVQAMKLGADNYLPKPANATQILSALHQDHAI
AESSLNSNEPLSKDSNETETEQDVLSVERLQWEHIQSVLAHHQGNISATARALGMHRRTL
QRKLSKKPKNK