Protein Info for B158DRAFT_1798 in Kangiella aquimarina DSM 16071

Annotation: diguanylate cyclase (GGDEF) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 670 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 429 to 450 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 461 to 631 (171 residues), 133.3 bits, see alignment E=3.4e-43 PF00990: GGDEF" amino acids 465 to 631 (167 residues), 127.6 bits, see alignment E=1.9e-41

Best Hits

KEGG orthology group: None (inferred from 69% identity to kko:Kkor_1142)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (670 amino acids)

>B158DRAFT_1798 diguanylate cyclase (GGDEF) domain (Kangiella aquimarina DSM 16071)
MVLAVIALGLIFAATQNVIAAEAEVKLEAENNDEGITLEDLQQLEPFPEFYDQLSPEARL
DWLNTQIDQAATPVQNYNYQRALAFEHFFNYRNMEAQEACQKNPPLSFDLRYRFACIQVS
DISYDNRLDKLLGLYQDAMEADNKEMVAQTLNSMGWYQSGHGDIELAFKSYEEALSMGEH
LEFYALNDAMVNTATLYIIHGDEEYVHKGIELLKKSIERTKDKLKEEGRTGDIPNTIIIP
QFNIGVAYALHVYDYEKALEWFTIVNNSKTSIPHLRMSSLLFSALSAVELGREQEAQRFL
ARSYDEPDVNNSEFSYLYCYQTLVRYKLGQPVDFDVCLPLHENVPLEVKIDVYKRISNLE
DDGIRYAGMEQFYKLFEDKLESQIKQSSTSVASTAELHRQQQESRLRNELLEKEIALKTA
QQEQREGQIRFMIAAVLALLLLVLITVIRLRQKRRLAEQFEELSVIDVLTGLKNRRFLEQ
NIGREFSFIKRSRAKGGQEALGIYLLDIDHFKRINDTYGHEVGDTVLIEFTRRINEAIRE
TDLFVRWGGEEFLLVARLENLDGLNVLAQRLRKAITELPYNIGSNQTIDLTATIGSVAYP
CLYNKEEDISWNKLVLLADQALYYGKHKQRDCWVSIQSIPDRKSLKVILNQALDKSVEDK
IISINSSIES