Protein Info for B158DRAFT_1779 in Kangiella aquimarina DSM 16071

Annotation: ATP-dependent helicase HrpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1319 TIGR01967: RNA helicase HrpA" amino acids 36 to 1312 (1277 residues), 1478.6 bits, see alignment E=0 PF00270: DEAD" amino acids 113 to 258 (146 residues), 30.5 bits, see alignment E=9.1e-11 PF00271: Helicase_C" amino acids 308 to 430 (123 residues), 49 bits, see alignment E=2e-16 PF04408: HA2_N" amino acids 493 to 520 (28 residues), 25.1 bits, see alignment (E = 4.2e-09) PF21010: HA2_C" amino acids 521 to 579 (59 residues), 35.2 bits, see alignment (E = 4.6e-12) PF07717: OB_NTP_bind" amino acids 652 to 727 (76 residues), 58 bits, see alignment 2.8e-19 PF11898: DUF3418" amino acids 741 to 1312 (572 residues), 516 bits, see alignment E=4.7e-158

Best Hits

KEGG orthology group: K03578, ATP-dependent helicase HrpA [EC: 3.6.4.13] (inferred from 88% identity to kko:Kkor_1161)

Predicted SEED Role

"ATP-dependent RNA helicase HrpA (EC 3.6.4.13)" (EC 3.6.4.13)

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1319 amino acids)

>B158DRAFT_1779 ATP-dependent helicase HrpA (Kangiella aquimarina DSM 16071)
MSKTPNDSSKEASTKPGIENNKNSHNNSPPIQKLIAEQLADCQLVDQFELSKLKSVITKR
QKNNQPVSKLINKAQQLLTDSMRIVEQRKQIIPKDIEYDLALPVCQARDDVRKAVEENQV
VVIAGETGSGKTTQLPKICLQLGLGVYGKIGHTQPRRVAATSVARRIAEELKTDLGEVVG
YSIRFNDQSNPVTPVRVMTDGILLNEITHDPLLRQYDTLIIDEAHERSLNIDFLLGYIKN
ILPKRPDLKVIITSATIDVERFARHFELDGKPAPILEISGRTYPVDVWYRPDDEENPSPQ
VERIGHAVDELINYAPGDILIFLSGEAEIRETAKFLRKERFQGCEVLPLYARLSMREQEK
IFHPSGGKRRIILSTNVAETSVTVPGIRFVIDPGFARISRYSVRNKIQRLPIEKISQASA
NQRKGRCGRVAEGVCIRLYEEEDFLNRPEFTDAEILRTNLAAVILQMKQLGLGDIEAFPF
IDEPAPKQISDGLNLLSELQAVDAKKQLTAIGRKMARLPIEPRLARILLAAQDESCIREA
LILAAFLSVKDPREWPFEKRELAQQKHAKYRHPQSDFIAIINLWDHLHQQQEDLSNNAFR
RYCQEELINFNAYREWRSTYRQLKTLVKSEHHQTQKQAEPINPDDKVYYAKLHSILLTGL
LSFIGQKDIEKGYLGTRQTRFMIHPQSANFKKQPPWVMAFEIVETTQNYARLTAMIETPW
IERIGGHLIKSHYFDAHWEKKRGAVVASLQQTLLGLKIVSNRTVDYSAVEPELCRELFIL
HGLVRRELDVRHDFQQKNEQLWHEVEQEVAKARQADMRADERDLIAWFDKRLPESICNVK
QLNQWLKKNKQQNNQLLSLNKDVLFKAEEQDANLYPETLTVNYIELPLSYHFEPGHPTDG
VTVKIPLSLSQQFKDSDFERLVPGLLEEKIEFMLRSLPKRFRKNFVPIPQFAQACYEQVL
EQQGSLIDIISRHLFKMTGVILPKEAWQELSLPEHYLMRFEIVDDKGKTLKSGRSLEQSQ
DIKKAKISVSKKKNSKPQTYTSWPDDFVKDGMVEEAGTKIPVTYALEDCGDKVRSIAVVN
KKQAQNVHVRGVCRLLALEKASLLGYMKKKYHNKQKLTLSVSTLGSVDELIDDAAMACLR
ALVESDVPYKKSEYQTLSQKAEKELVPAATAMLDDLVQVLQLRATVLAEAKGMGKSLAST
RKDIIGQCDYLFQPGFCFRFGAEKIKDFKRYLSAVEKRIERAKLNPLKEAESLIAISDWV
DVRESLAQDKAIPAFEVDEFNWMLEEFRISLFAQGQKTRFPISAKRLQKQLDELEKIYY