Protein Info for B158DRAFT_1479 in Kangiella aquimarina DSM 16071

Annotation: aminopeptidase N, Escherichia coli type

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 888 TIGR02414: aminopeptidase N" amino acids 14 to 887 (874 residues), 1276.1 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 38 to 200 (163 residues), 62.5 bits, see alignment E=1.2e-20 PF01433: Peptidase_M1" amino acids 240 to 451 (212 residues), 191.1 bits, see alignment E=4.2e-60 PF11940: DUF3458" amino acids 458 to 561 (104 residues), 105.9 bits, see alignment E=2.4e-34 PF17432: DUF3458_C" amino acids 565 to 887 (323 residues), 376.8 bits, see alignment E=2.1e-116

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 86% identity to kko:Kkor_1489)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.2

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (888 amino acids)

>B158DRAFT_1479 aminopeptidase N, Escherichia coli type (Kangiella aquimarina DSM 16071)
MKTSDSISVKYRKDYKPSAFLINKVSLNFELFDDYAIVTARMMLQANPAAESSGALVLDG
EELELQGIEVAGQKLVQEQYEVDSEQLTIWLNKIDGLDYQQASFELVTKVKIYPAQNTSL
EGLYLSSEKFCTQCEAEGFRKITYYLDRPDVMSTFTVRIEAEKKKYPHLLSNGNQIEHGS
LANGRHYAIWQDPFRKPSYLFALCAGDYDLLEDHFTTRSGREIKLEIYVDKGKLEQCHHA
MESLKKSMAWDEEVFGLEYDLDIYMIVAVGDFNMGAMENKGLNIFNTKYVLAHPETATDQ
DFEDVEAVIAHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQQFTADQTDHAVKRIEDVK
VIRSHQFAEDAGPMAHPIRPDSYIEMNNFYTVTVYNKGAEVIRMYHTLLGTDGFRRGMDL
YFERFDGQAVTCEDFVSAMEDANDYDLIQFRRWYSQAGTPEVTVTSEYDELHKKLTLQIG
QACPDTPGQSNKQPFHIPLKLGLLDKDGNDLPLELASNKEQLTGDILHLTEAEQTFEFVG
VSHKPVLSLLRNFSAPVRLFYDYNDQELAFLYAHDKDSFNRWEAGQRLFARVIWQLCAEQ
EAGEPMQFPLHLVNAVQNLLSDESLDGRFKALALTLPDIKALIEEVERVNLDHLIAAHDF
LKRELAKQLEMDWLVHYQANHHVGAFKQDKAAIAKRAFAGVCLSYLVALDKPKAYELAVS
QLVNSNNMTDAETALQLLMHSNYSQKEQIADDFYRKWQNEELVVNKWLSAQATDPTDSTI
ERVKGLIEHPAFDIKNPNKVRSVVGAFAGSNLPQFHRNDGKGYVFLAEQIKQLYSVNPQT
AARLTGAFNRWKKFDDERQRLMCEQLQGILQLPDLSKDVYEIASKALG