Protein Info for B158DRAFT_1437 in Kangiella aquimarina DSM 16071

Annotation: imidazolonepropionase (EC 3.5.2.7)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01224: imidazolonepropionase
  • amino acids 30 to 404 (375 residues), 483.6 bits, E=1.8e-149
• PF01979: Amidohydro_1
  • amino acids 72 to 392 (321 residues), 84.7 bits, E=7.6e-28
• PF07969: Amidohydro_3
  • amino acids 121 to 389 (269 residues), 51.7 bits, E=1e-17

Best Hits

Swiss-Prot: 62% identical to HUTI_PSESM: Imidazolonepropionase (hutI) from Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)

KEGG orthology group: K01468, imidazolonepropionase [EC: 3.5.2.7] (inferred from 88% identity to kko:Kkor_1528)

MetaCyc: 61% identical to imidazolonepropionase (Pseudomonas fluorescens)
Imidazolonepropionase. [EC: 3.5.2.7]

Predicted SEED Role

"Imidazolonepropionase (EC 3.5.2.7)" in subsystem Histidine Degradation (EC 3.5.2.7)

MetaCyc Pathways

• L-histidine degradation II (5/5 steps found)
• L-histidine degradation VI (7/8 steps found)
• L-histidine degradation I (3/4 steps found)
• L-histidine degradation III (4/6 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.2.7

Protein Sequence (409 amino acids)

>B158DRAFT_1437 imidazolonepropionase (EC 3.5.2.7) (Kangiella aquimarina DSM 16071)
MSQPETKPFDYLIHNVNIASMATHGDYGIIENACLGVKSGVIEFIGTQEQLNAANELESN
AETVINAHNQWLTPGLIDCHTHLVYGGNRANEFEMRLNGASYEEIAKAGGGILSSVRATR
AATEQQLFETASKRLKSLLKEGLTTIEIKSGYGLDTETEIKMLKVARRLGKEFPVRVSTT
FLGAHALPPEYKDRADDYIDLVCNEMLPTIAELELADAVDAFCENIGFSYQQTQKVFETA
KQLGLPVKLHAEQLSDQSGAGLAADFDALSADHLEYLSQESIEKMAKSGTVAVLLPGAFY
FLRETKLPPIQALRDKQVPMAIATDSNPGTSPAESLLLMLNMACTLFRMTPLESLQGVTI
NAAKALGLSKEIGTLEVGKKADMVLWDIDHPNQLSYQLGGSNWTRTFKG