Protein Info for B158DRAFT_1405 in Kangiella aquimarina DSM 16071

Annotation: Cation/multidrug efflux pump

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1061 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 340 to 357 (18 residues), see Phobius details amino acids 363 to 383 (21 residues), see Phobius details amino acids 390 to 417 (28 residues), see Phobius details amino acids 437 to 456 (20 residues), see Phobius details amino acids 465 to 487 (23 residues), see Phobius details amino acids 546 to 569 (24 residues), see Phobius details amino acids 881 to 900 (20 residues), see Phobius details amino acids 907 to 927 (21 residues), see Phobius details amino acids 933 to 958 (26 residues), see Phobius details amino acids 979 to 997 (19 residues), see Phobius details amino acids 1009 to 1036 (28 residues), see Phobius details PF00873: ACR_tran" amino acids 12 to 1036 (1025 residues), 564.4 bits, see alignment E=4.4e-173 PF03176: MMPL" amino acids 874 to 1043 (170 residues), 27 bits, see alignment E=2.2e-10

Best Hits

KEGG orthology group: None (inferred from 96% identity to kko:Kkor_1558)

Predicted SEED Role

"Acriflavin resistance protein" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1061 amino acids)

>B158DRAFT_1405 Cation/multidrug efflux pump (Kangiella aquimarina DSM 16071)
MVKQYDTHSGIISWFARNSVAANLLMIFIIVAGFIGLSHLRQQVFPDIIINSVSIQVPYP
GAAPQEVEEGIVILIEENIKDIEGIKKVTSTASEGMGSINIEIEDNYEVSEVMDEIKVRV
DAIPNLPDLAERPVIYENRMQRQVMRLNVFGDANERTLKEYAKDIKDELLALPHVSLVEV
EGARPYEVGIQVSDYQLRKYGLTLQDVANAVRSHSLDLPSGTIKTLGGDILVRTKNQAYD
AYDFAKIPVITRPDGTTLLLADIAAIDDGFAEWNFLSRFDGKPTVSLRVRSSLESDDLLI
AEQIYSYLDKKTPTLPAGISIEAWGDGTYYLKGRLEMMQKNMLAGIILVFIVLALFLRFK
LAFWVMIGIPLCFLGAFALMYMYPGFAMTINMITLFGFILVLGIVVDDAIIIAESAWASI
EEKGHSIDSVVEGAKRVALPATFGVLTTIAAFYPMLAISGPWSNAMASMGLVVMFCLMFS
LIESKLILPAHLAHMKLNKLEDTKNPKVRAVKGFFRSIRLKVKDLLSRFINNVYKPKLET
FLNYRGLTILTFVCLLFITTIGFIGSGWVKTSLFPNIPNDGVFVEIKMAEGATAEQAMSN
VQIVWDKLNELHSEVEAEHGIGVFQHAFMWTRENTGAYMWTELVKSENLPINQFDLIDRW
RDKVGTLPAVEEISFGGGGGGPGGDGVGYRLVGTDIEELQIVTEKIRAKLAEYDGVYDIS
DNLSGGKEEIVVEVKPHGYNLGLSTQILSQQVRNAFYGSEAQRFLRDNEEVKVFVRYPLD
DRRSIGNLEQMPIRTPSGEYVTFTDVANYDVQEGFSRISRIDGVRANRISADVSPQAAIT
SGEIHEDMMQNVIPDILAQHPTVKLEPGGPSEDQQKLTKELGIGGLIALILIYGLMAIPL
KSYIKPVVVMSAIPFGIIGAMVGHLLLDINLSMFSFFGIIALSGVVVNDSLLMVDFIGRA
RAEGMSRIEAAINAGTRRFRAIILTSLTTFFGLLPITTETSLQAQLVIPMAVSLAFGIVF
ATVITLIWVPCLYVTLGSIKDWFLGRDAKSLSNKEEAYENN