Protein Info for B158DRAFT_1314 in Kangiella aquimarina DSM 16071

Annotation: Zn-dependent dipeptidase, microsomal dipeptidase homolog

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01244: Peptidase_M19
  • amino acids 56 to 414 (359 residues), 321.4 bits, E=3.1e-100

Best Hits

KEGG orthology group: K01273, membrane dipeptidase [EC: 3.4.13.19] (inferred from 90% identity to kko:Kkor_0971)

Predicted SEED Role

"putative periplasmic dipeptidase"

MetaCyc Pathways

• leukotriene biosynthesis (2/6 steps found)
• gliotoxin biosynthesis (2/9 steps found)
• peptido-conjugates in tissue regeneration biosynthesis (6/17 steps found)
• arachidonate metabolites biosynthesis (3/74 steps found)

Isozymes

Compare fitness of predicted isozymes for: 3.4.13.19

Use Curated BLAST to search for 3.4.13.19

Protein Sequence (422 amino acids)

>B158DRAFT_1314 Zn-dependent dipeptidase, microsomal dipeptidase homolog (Kangiella aquimarina DSM 16071)
MKKTFLSTLVVAISLSALTACQQEESTEQPVNTEVVAEVKVAEKPVDYGVKAEAISKKYI
IADTHIDVPHRLLEKYDDVSMATEGGDFDYPRAVKGGLDAPFMSIYTPADLEEKGGSKEQ
AEQLIDMVEKMVADSPDKFALAMSPGDLLRNFRQGLISLPMGMENGSPLEGDLGNVEYFF
ERGIRYITLAHSLSNHLSDSSYDEARPNDGLSEFGREVVKEMNRLGMMVDVSHLSDKAFH
DVLEVSEVPVIASHSSARHFTPGFERNMSDEMIKALADNGGVIFINFGSTFVSQASRDNY
DAYKEARQQFMEENGVTAEHESVMEFTKQYRAEKPFEFADLEIVLDHFDHVIKLVGVDYV
GIGSDYDGVGDSLPTGLKDVATYPNLIEGLLVRGYSEEEIAKILSGNLLRVWTQVENHAQ
QQ