Protein Info for B158DRAFT_1299 in Kangiella aquimarina DSM 16071

Annotation: Uncharacterized conserved protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01513: NAD_kinase
  • amino acids 5 to 164 (160 residues), 72 bits, E=8.9e-24
• PF00781: DAGK_cat
  • amino acids 74 to 138 (65 residues), 21.8 bits, E=1.9e-08
• PF20143: NAD_kinase_C
  • amino acids 231 to 368 (138 residues), 41.3 bits, E=1.9e-14

Best Hits

KEGG orthology group: None (inferred from 85% identity to kko:Kkor_0957)

Predicted SEED Role

"ATP-NAD kinase (EC 2.7.1.23)" (EC 2.7.1.23)

MetaCyc Pathways

• NADP biosynthesis (1/1 steps found)
• NAD phosphorylation and transhydrogenation (1/2 steps found)
• NAD phosphorylation and dephosphorylation (1/3 steps found)
• cytosolic NADPH production (yeast) (2/5 steps found)
• mitochondrial NADPH production (yeast) (2/5 steps found)
• NAD(P)/NADPH interconversion (2/6 steps found)
• superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) (3/8 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.23

Use Curated BLAST to search for 2.7.1.23

Protein Sequence (373 amino acids)

>B158DRAFT_1299 Uncharacterized conserved protein (Kangiella aquimarina DSM 16071)
MFHLGFIVNPFAGIGGKVGLKGSDGEAIRAEAFARGAVSQSANRARITLEILKPYKDQLT
FFTASGDMGENLLKELGFNYECVYSYEGASTAQDTIEAANKIVAKKANLFLFAGGDGTAR
NIYEAVGEELPVLGIPAGVKIHSGVYAVTPKAAGLVIEQMLNNELVSLLETSVMDIDEEA
FRKGNVRAKKYGEMQVPAEHRYVQSTKSGGKEVEALVVQDIADYVVEQMEDDVHYLIGSG
TTCAAVMDSLGLENTLLGIDHVFQQRLVQPDVYEKHILELLEAHPEKVKAVITIIGGQGH
IIGRGNQQLSAKVLRQLGRDNLIVIATKTKLQQLNGKPLIVDSDDLALNEEFSGPIKVIT
GYEDSVLYPVGRI