Protein Info for B158DRAFT_1160 in Kangiella aquimarina DSM 16071

Annotation: tRNA-adenosine deaminase (EC 3.5.4.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 159 PF00383: dCMP_cyt_deam_1" amino acids 6 to 105 (100 residues), 98.7 bits, see alignment E=1.6e-32 PF14437: MafB19-deam" amino acids 9 to 153 (145 residues), 125 bits, see alignment E=2.1e-40

Best Hits

Swiss-Prot: 52% identical to TADA_ECOL6: tRNA-specific adenosine deaminase (tadA) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K11991, tRNA-specific adenosine deaminase [EC: 3.5.4.-] (inferred from 84% identity to kko:Kkor_1829)

MetaCyc: 52% identical to tRNA adenosine34 deaminase (Escherichia coli K-12 substr. MG1655)
3.5.4.-

Predicted SEED Role

"tRNA-specific adenosine-34 deaminase (EC 3.5.4.-)" in subsystem tRNA processing (EC 3.5.4.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.4.-

Use Curated BLAST to search for 3.5.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (159 amino acids)

>B158DRAFT_1160 tRNA-adenosine deaminase (EC 3.5.4.-) (Kangiella aquimarina DSM 16071)
MTDFTEFDHNCMQRAFELAAIAEEKGEVPVGAVLAKEGEIISEGFNQPILSHDPTAHAEM
VALRAAGAQIENYRLVNSTLYVTLEPCAMCAMAMVHARVARVVFATPDPRTGAAGSVLNI
LQNPNFNHQCQVESGLLQDDCSEQLKRFFRNKRKSSDKK