Protein Info for B158DRAFT_1125 in Kangiella aquimarina DSM 16071

Annotation: Holliday junction DNA helicase subunit RuvA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 TIGR00084: Holliday junction DNA helicase RuvA" amino acids 1 to 203 (203 residues), 190.5 bits, see alignment E=1.1e-60 PF01330: RuvA_N" amino acids 1 to 63 (63 residues), 66.2 bits, see alignment E=5.6e-22 PF14520: HHH_5" amino acids 73 to 128 (56 residues), 55.6 bits, see alignment E=1.5e-18 PF07499: RuvA_C" amino acids 159 to 204 (46 residues), 56 bits, see alignment 1.1e-18

Best Hits

Swiss-Prot: 58% identical to RUVA_AERHH: Holliday junction ATP-dependent DNA helicase RuvA (ruvA) from Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)

KEGG orthology group: K03550, holliday junction DNA helicase RuvA (inferred from 94% identity to kko:Kkor_1863)

Predicted SEED Role

"Holliday junction DNA helicase RuvA" in subsystem DNA-replication or RuvABC plus a hypothetical

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (205 amino acids)

>B158DRAFT_1125 Holliday junction DNA helicase subunit RuvA (Kangiella aquimarina DSM 16071)
MIGRIRGTLIEKIPPFVIIETSAGVGYEIQVPMTTFYQLPEEGEQAILSTHMSISENLHA
LYGFISTKDRALFRELIKVNGVGPKLALGILSGMESDEFVMTVHDGNVDRLVKLPGVGKK
TAERLLVEMSDRLKDWSISAGLSSSKPSETTIPAGAKTDASQEAVSALIALGYKPQIASK
AVAQVAHDDAKSEELIRLALRQLAG