Protein Info for B158DRAFT_0948 in Kangiella aquimarina DSM 16071

Annotation: RND family efflux transporter, MFP subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 51 to 384 (334 residues), 165.4 bits, see alignment E=8.3e-53 PF16576: HlyD_D23" amino acids 69 to 288 (220 residues), 61.2 bits, see alignment E=1.4e-20 PF13533: Biotin_lipoyl_2" amino acids 76 to 120 (45 residues), 28.5 bits, see alignment 1.5e-10 PF13437: HlyD_3" amino acids 199 to 292 (94 residues), 49.3 bits, see alignment E=1.1e-16

Best Hits

KEGG orthology group: K02005, HlyD family secretion protein (inferred from 79% identity to kko:Kkor_2032)

Predicted SEED Role

"Probable RND efflux membrane fusion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (393 amino acids)

>B158DRAFT_0948 RND family efflux transporter, MFP subunit (Kangiella aquimarina DSM 16071)
MKQKLMKGLAINKLLDHKRTAALIAIMLPLALLFIYVVVRSGPLAPTLVTQIQVSKVSIS
PALFGIGTVEARYQYKVGPTIPGRVQTLKVDIGDQVTKGQLLGVMDSVDLEQRMEAQQSA
LMQAKAKLQEAQTRYQFSDEQFKRYQKLLESNSISEEQFLVKQQDYHIAEAGLAAARQEL
LRQEAEQKAMQAQQHNLDLISPIDGIVVKRNAEQGTTVVAGQSVIEIINPEDIWINVRFD
QIHSTGLNPGLTALVNLRSKSKLDLSGKIYRVEPIADAVTEEFLAKVTIDELPQPLPSIG
ELAEVTIELDSLPSTTVIPNAALKRIDGELGVWKIIDGDIEYVPVSIGATDLDGLVEIKK
GLSLGESVVLHSEKALTANSRIKVVESLVGKDK