Protein Info for B158DRAFT_0836 in Kangiella aquimarina DSM 16071

Annotation: Type II secretory pathway, component ExeA (predicted ATPase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 577 transmembrane" amino acids 31 to 50 (20 residues), see Phobius details amino acids 285 to 304 (20 residues), see Phobius details PF13191: AAA_16" amino acids 22 to 157 (136 residues), 50.7 bits, see alignment E=7.8e-17 PF13401: AAA_22" amino acids 42 to 172 (131 residues), 95.6 bits, see alignment E=7.6e-31 PF13245: AAA_19" amino acids 45 to 164 (120 residues), 26.9 bits, see alignment E=1.2e-09 PF21327: GspA_C39-like" amino acids 389 to 486 (98 residues), 33.8 bits, see alignment E=1e-11

Best Hits

Predicted SEED Role

"General secretion pathway protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (577 amino acids)

>B158DRAFT_0836 Type II secretory pathway, component ExeA (predicted ATPase) (Kangiella aquimarina DSM 16071)
MYNDFFGLKETPFTIAPDPRYLFMSERHRDALAHLLYGIGAGGGFVLLTGEVGTGKTTVC
RCLLEQLPANVRLAYILNPKLNAIELMATMCDELGIEYDPRESSLKTFTDLLSRRLLDNH
EQGLNTVLMIDEAQNLSVEVLEQIRLLTNLETNQKKLLQIILIGQPELQELLAKKELRQL
AQRITARYHLRPLSLNETKSYLEHRLRIAGVMRPVFKGKAIKLIHKASGGIPRLINVISD
RAMLGAFAENLHHVDVRTVNKAVSEVLGEKTDMAENGSLVNHWKWAVPTLLVGLTLGVTA
WSFGLFNDAVGTSSEQQPEHIAQLADSSQAASINEQTTKVGETDESSIKTNDVAGENVRE
NISKTPSELAEEFWGEQSWDRSGAIASQNLLALWGVSYLPFQSPDACSFAANYGLGCDQG
MTDWKFLSQLNRPANLKFTTAQGGDFWGTLIEIQDQSVVMQFGENQVMIERKKINPMWTG
EYRLFWKKPAGFRDPVGIGSRGAEIIWLTNFIEMSEGITIEPDNVFSEQVADWLALFQME
HGLISDGILGKHSIMMINNLAEPSIPKLFVERLQVEK