Protein Info for B158DRAFT_0826 in Kangiella aquimarina DSM 16071

Annotation: drug resistance transporter, Bcr/CflA subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 9 to 29 (21 residues), see Phobius details amino acids 46 to 65 (20 residues), see Phobius details amino acids 77 to 95 (19 residues), see Phobius details amino acids 101 to 123 (23 residues), see Phobius details amino acids 135 to 156 (22 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 217 to 241 (25 residues), see Phobius details amino acids 249 to 267 (19 residues), see Phobius details amino acids 279 to 304 (26 residues), see Phobius details amino acids 309 to 330 (22 residues), see Phobius details amino acids 342 to 362 (21 residues), see Phobius details amino acids 368 to 387 (20 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 12 to 384 (373 residues), 254.4 bits, see alignment E=1.2e-79 PF07690: MFS_1" amino acids 16 to 355 (340 residues), 159.2 bits, see alignment E=2e-50 PF06609: TRI12" amino acids 22 to 187 (166 residues), 24.8 bits, see alignment E=1.1e-09 PF00083: Sugar_tr" amino acids 43 to 181 (139 residues), 35.7 bits, see alignment E=7.3e-13

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 91% identity to kko:Kkor_2169)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (394 amino acids)

>B158DRAFT_0826 drug resistance transporter, Bcr/CflA subfamily (Kangiella aquimarina DSM 16071)
MTRSKINVAHLLPLLASMVAITPLAIDMYLPAMPIIAKELGTTSSAIQVSLSLYLAGYAL
GMMMFGPIADRIGRRKVALVGLTGFIITSLLLAFTESINQFLAYRFVQAAFGSGATVVVP
GIIRDLYKEHTAKGLSYVSLIMMVAPMIAPGIGSFILELSVWRTIFLSLAGYAVFILLLV
IWKLPKNLPLRSERKWLHEFASNYKLVFSHPASRLNIISSMMGSFGFFCYITTISFVYIE
YFGVSEGKFSILFGANVVALMITNIINTRTVERAGSARMLMIGTVIANIFALSLVLVTVF
GWSLYWTVGALFPLIGSLALITVNSDGLILNQFPQQTGTATAVIGTLRFGSGALAGPILA
LLFDGTPLNFAILMFASVAIVMIVQLIRRRLSLS