Protein Info for B158DRAFT_0805 in Kangiella aquimarina DSM 16071

Annotation: Cation/multidrug efflux pump

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1034 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 327 to 347 (21 residues), see Phobius details amino acids 353 to 371 (19 residues), see Phobius details amino acids 378 to 401 (24 residues), see Phobius details amino acids 425 to 447 (23 residues), see Phobius details amino acids 453 to 476 (24 residues), see Phobius details amino acids 520 to 542 (23 residues), see Phobius details amino acids 866 to 885 (20 residues), see Phobius details amino acids 892 to 912 (21 residues), see Phobius details amino acids 918 to 941 (24 residues), see Phobius details amino acids 967 to 984 (18 residues), see Phobius details amino acids 996 to 1020 (25 residues), see Phobius details PF00873: ACR_tran" amino acids 1 to 1020 (1020 residues), 600.5 bits, see alignment E=8.7e-184 PF03176: MMPL" amino acids 824 to 1019 (196 residues), 28.2 bits, see alignment E=1.4e-10 PF02355: SecD_SecF" amino acids 865 to 1015 (151 residues), 35.3 bits, see alignment E=1.2e-12

Best Hits

KEGG orthology group: None (inferred from 92% identity to kko:Kkor_2197)

Predicted SEED Role

"Acriflavin resistance protein" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1034 amino acids)

>B158DRAFT_0805 Cation/multidrug efflux pump (Kangiella aquimarina DSM 16071)
MIAWFARNPVAANLLMVVILVAGFFTISKRVPIETFPTTELQFINVVVPFRGATPEEVEQ
TISTRVEEAIYDLDGIKQLTSTSSENVSRVTIEVEEDYDVKELLDEIKSRVGALNTLPLE
AERPIIQQVERRRETISVVVSGNLPEKELRQYSEIIQEELSSIPGLTQIETSGARAFEIA
IEVNQSLLNEYGLTLQDIANAINSRSLDLSAGQVKSERGEILLRLKAQSYTQEQFEQVPI
LTREDGTILMLKDLAVIKDGFEEESLNTRFDGKPSIELEIYRTGDQSAIEVAQRVKDYVA
AKKSDLPAGVDLSIWRDRSKSVNARLNTLISSAVQGGLLVILLLALFLRPSIAMWVSFGI
PIAFAGGMALMPEMGVTVNLISLFAFILVLGIVVDDAIVTGENIYNHLNRGASPLDAAIN
GTKEVAVPVTFGVITTMAAFVPLSFIGGGWGTFYSSIPLIVIPVLIFSLVESKLILPAHI
GHMKKLNAKNDNKLVQYQQKFAKGFEDFVMRFYKPALKFALAHWQLTLAIFLAFALLIWA
AVSSGLTRFIFFPRIQSEIARATLVMPEGTPFELTDSYVERMTEAALELKDKYREEDGSS
IVEHIFSVSGYGGGGGAVSSSNGLVMFEITAPEERESDITSAELVNEWRKLIGPLPGVES
LTFRAEIGRNRDPIDVQLRGSNIQRLSGAAMEVKEMLGDISGVFDISDSFSKGKQEIQFS
LKPQAETLGLTLSDLARQVRSSYFGVEVQRVQRGREDVRVMLRLAKEERSTLDGLNSLLI
QTPSGAKVPLEQLAELSYGNSPSSITRINRQRTLNITADVQKETADIEAIKRRIHQETTE
ILERYPGVSYSLEGEAREQEESTSRLTTSLMFVLFAIYILLAIPFKSYVQPFIVMSVIPF
GACMAIVGHWIMGMSLSVMSLMGMLALTGVVVNDSLVLVDYINQQRRKHGESLLDAVLHA
GVRRLRPVMLTSLTTFAGLMPLIFEKSTQAQFLIPMGVSLGFGILFSTLITLVLVPLLYY
KSAQVKQYFKRKMA