Protein Info for B158DRAFT_0723 in Kangiella aquimarina DSM 16071

Annotation: diguanylate cyclase (GGDEF) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 689 transmembrane" amino acids 21 to 50 (30 residues), see Phobius details amino acids 56 to 72 (17 residues), see Phobius details amino acids 84 to 104 (21 residues), see Phobius details amino acids 111 to 135 (25 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 426 to 444 (19 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 522 to 685 (164 residues), 147.6 bits, see alignment E=1.4e-47 PF00990: GGDEF" amino acids 525 to 683 (159 residues), 131.1 bits, see alignment E=1.6e-42

Best Hits

KEGG orthology group: None (inferred from 78% identity to kko:Kkor_2281)

Predicted SEED Role

"diguanylate cyclase (GGDEF domain)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (689 amino acids)

>B158DRAFT_0723 diguanylate cyclase (GGDEF) domain (Kangiella aquimarina DSM 16071)
MALLFNSFLIAHLYGNLSLHFGQIFIIFCLVTRGLYPAVFAALIGSIGLYVETHNPAFFI
NSILEILVLYALSRRGWVLLVADVVYWLVIGIPITYVFVIYFFGISSSDFIQVIMLKQLL
NGVLVVSAASLLRPFLPTRWHRLDIQQQLPKLSYRIFELSMISILLPSLIITLILSNNSA
KIAEQQASELLGVQADHYTEITRNHLTHHQRMVDNLANTFSWQPYKDKEKLEFLLDAQSQ
YPDVFSMLITDENGYVIHGAPQEFEDTLQGLSRAEKMVDDRLYFQVPYSRNTHYISDVFQ
ARGYGNDPIVAISSPYFEGEQFSGIVQATLNLANFEKFGAGTSGFSVFVIVTDAKNKLVY
ASEILNLEPLSEFLPEKIEQVYTDELPLLKLSEGFFLFKNRVTEGGWKIYTLSSPDTLID
AYKNDFYNLIVSLLIIASIVLLVVQKFSKQITRPLETIVRHFSSNEPIPRKARSIYSSVE
IESVREQLQQAQHFMLEYQKTLQEQVEEKTKELREANDKLALVSVQDELTQIYNRRGFDQ
NVKNAFAVSIRHATPITMAILDIDHFKNVNDQWGHAAGDQCIIMVAEEMKKRFKRDSDFV
ARYGGEEFVVFIAGGDINIHRQMLDELRLNIANHEIYYEEKIISITVSIGAYSVKDDLNI
TYDKLVSNADKLLYKSKTSGRNQLSAGQQ