Protein Info for B158DRAFT_0690 in Kangiella aquimarina DSM 16071

Annotation: general secretory pathway protein E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 TIGR02533: type II secretion system protein E" amino acids 24 to 506 (483 residues), 719.8 bits, see alignment E=7.7e-221 PF00437: T2SSE" amino acids 135 to 401 (267 residues), 369.6 bits, see alignment E=4e-115

Best Hits

Swiss-Prot: 70% identical to GSPE_PSEAE: Type II secretion system protein E (xcpR) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 94% identity to kko:Kkor_2315)

MetaCyc: 59% identical to type II secretion system protein GspE (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"General secretion pathway protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (509 amino acids)

>B158DRAFT_0690 general secretory pathway protein E (Kangiella aquimarina DSM 16071)
MAEQMATKQSEHETEAVTKEVGFRPLPFSFAKRHGVFLIRTDDGMQCYMREGTAPQALLE
VRRHYPHRFQIEKLNETEFESRLSAFYQSGTADARQTMEDLGDEMDLFRLAEEMPETEDL
LEAEDDAPIIKLINALLTEAIKENASDIHIETFEKTLSVRFRVDGVLREVLQPNRKLAPL
LVSRIKVMGKLDIAEKRIPQDGRIALRIANRAVDVRVSTMPSSFGERVVLRLLDKEAGRL
EFSHLGMEPKTMQLMSDLLHKPHGIILVTGPTGSGKTTTLYAGLSLLNNSTRNILTVEDP
IEYLIDGIGQTQVNPKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLV
LSTLHTNTAIGAVTRMQDMGVEPFLLSTSLLGVLAQRLVRRLCPECKKPAVANQKECELM
GFDASNPPTIYHPDGCEACNYHGYRGRQGIYELVMIDDQMRTMIHNNNSEQEMERHARKF
TPSIRADGRQRVLEGMTSVEEVLRVTRED