Protein Info for B158DRAFT_0664 in Kangiella aquimarina DSM 16071

Annotation: ADP-heptose:LPS heptosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 PF01075: Glyco_transf_9" amino acids 76 to 296 (221 residues), 159.5 bits, see alignment E=4.8e-51

Best Hits

KEGG orthology group: K12982, heptosyltransferase I [EC: 2.4.-.-] (inferred from 87% identity to kko:Kkor_2339)

Predicted SEED Role

"ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-)" in subsystem LOS core oligosaccharide biosynthesis (EC 2.4.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.-.-, 2.4.1.-

Use Curated BLAST to search for 2.4.-.- or 2.4.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>B158DRAFT_0664 ADP-heptose:LPS heptosyltransferase (Kangiella aquimarina DSM 16071)
MLKDFPQSPQAICILRLSAIGDVCHAVSTVQAIQRQYPEALITWVIGKVEAQLLKNLPGV
EFIVFDKIKGIKAYAELRKVMKERQYDILLHMQLAFRANLAAYFIPAKIKLGFEKKRSKE
LHSLFVNHHITDSKGMHVLEGFRDFARAIGVPDSDPLWNIPLPREIELWAENQLPQEPFI
VISPGASKAERNWLAARYAKVADYCHSKGFKVVMTGGPSTMERELGDSILSHSKSPIIDM
IGQTNLKQLLATLKAAQCVIAPDSGPAHMAVTQGTPVIGLYAHSNPRRTGPYLYLDYVAD
AYTKNATQQLNCNVEDLPWGYRLKGDNLMQQISVEQVTRLVDQVIENVLNKNVVDQNSYQ