Protein Info for B158DRAFT_0624 in Kangiella aquimarina DSM 16071

Annotation: Fatty-acid desaturase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00487: FA_desaturase
  • amino acids 49 to 273 (225 residues), 82.1 bits, E=2.9e-27

Best Hits

KEGG orthology group: K00507, stearoyl-CoA desaturase (delta-9 desaturase) [EC: 1.14.19.1] (inferred from 91% identity to kko:Kkor_2378)

Predicted SEED Role

"Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)" (EC 1.14.19.1)

MetaCyc Pathways

• palmitoleate biosynthesis IV (fungi and animals) (2/2 steps found)
• oleate biosynthesis II (animals and fungi) (1/2 steps found)
• sorgoleone biosynthesis (2/8 steps found)

KEGG Metabolic Maps

• Biosynthesis of unsaturated fatty acids

Isozymes

Compare fitness of predicted isozymes for: 1.14.19.1

Use Curated BLAST to search for 1.14.19.1

Protein Sequence (303 amino acids)

>B158DRAFT_0624 Fatty-acid desaturase (Kangiella aquimarina DSM 16071)
MKMKQWFDNSQINTDTNQPEQLEGVDWPRVIPYIGLHLVCLFAFVTGVSWTAVIICIAAY
LIRMFAITAFYHRYFSHKSFKTYRWVQAVFGFLGASATQRGPLWWAAHHRHHHIYADTDE
DAHSPRHGFLKSHMLWFLNKKNFPTQEGRVKDLAKYPELRWLDRFDIFPPIIFAALIFGL
GVYLEMFHPELGADRWQVLIWGFFISTILLSHVTYCINSLAHRWGSKRFETNDDSRNNFL
LALLTLGEGWHNNHHFSPGSVKQGFYWWEIDLSFYVLKAMEKLGLVWDLKYPNKELIALK
AKS