Protein Info for B158DRAFT_0395 in Kangiella aquimarina DSM 16071

Annotation: K+ transport systems, NAD-binding component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF13241: NAD_binding_7" amino acids 2 to 88 (87 residues), 22.4 bits, see alignment E=9.1e-08 PF02254: TrkA_N" amino acids 3 to 124 (122 residues), 93 bits, see alignment E=9.8e-30 amino acids 234 to 349 (116 residues), 92.8 bits, see alignment E=1.1e-29 PF02080: TrkA_C" amino acids 154 to 224 (71 residues), 43.9 bits, see alignment E=1e-14 amino acids 390 to 450 (61 residues), 34.9 bits, see alignment E=7.1e-12

Best Hits

Swiss-Prot: 64% identical to TRKA_VIBAL: Trk system potassium uptake protein TrkA (trkA) from Vibrio alginolyticus

KEGG orthology group: K03499, trk system potassium uptake protein TrkA (inferred from 99% identity to kko:Kkor_2621)

Predicted SEED Role

"Trk system potassium uptake protein TrkA" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>B158DRAFT_0395 K+ transport systems, NAD-binding component (Kangiella aquimarina DSM 16071)
MKIIILGAGQVGTTLALNLEGEDNDITLIDTDSKRLRDIQDHLDLRTITGHGAYPDVLYN
AGIEDADMLVAVTNSDEVNMIACQIAHSLYQTPTKIARIRSPNYHNKDIIFKDNHIPVDV
VISPEKLVTQYITRLIENPGAFQVLDFAEGKVRLVAVRAYYGGPLVGNALSELKHHLPNV
DTRVAAIFRRGAPIVPTGHTIIEADDEVFFLAAKKHIRSVMSELQRLEKNYTRVMIAGGG
NIGEGLAKALESKMQVKIIERSPERAQELADVLHDTLVLQGDVSDEDMLKDENIGDFDLF
ISVTNDDEANIMSALLAKKLGVRKTMVLINRTAYVDLIQGHQIDIAISPQQVTIGSLLKH
IRRGLVSNVYSLRRGAAEAIEAVAKGNEQSSLVVGRTIGELPLPPGTSIGAIVRDDQVLI
AHENIIIRENDHVVLFMVDKAYIHDVERLFQVNVTYF