Protein Info for B158DRAFT_0335 in Kangiella aquimarina DSM 16071

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 25 to 28 (4 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details PF00672: HAMP" amino acids 198 to 250 (53 residues), 45.9 bits, see alignment 8.8e-16 PF00512: HisKA" amino acids 255 to 319 (65 residues), 53.3 bits, see alignment E=3.5e-18 PF02518: HATPase_c" amino acids 366 to 477 (112 residues), 75.9 bits, see alignment E=5.2e-25

Best Hits

Predicted SEED Role

"Sensory histidine kinase BaeS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>B158DRAFT_0335 Signal transduction histidine kinase (Kangiella aquimarina DSM 16071)
MQIRYKQFFVILVANLLLAAALFTAISWNFNRSFQEYVRNDQAKELQPLVEGLAEAYQQK
GRSWQWLHNNRRQWQRLVQQYLIREAEPDSQVIEVSQSTQRPPRKPRPPHPMTQRLLLSD
AHDNPIIELPVINPEHRKTSIQWLPIMIDGEVIGQLGVAHSTELEREMDRLFVTHQLQQS
AWIVLGILLISVGLAFPFAKRLVRPVTRLQESMQQLAGGKIEQLEPLPVTSDDELGRLAH
AFNLLTDTLKDNLKARQQWIADISHELRTPVAILQGELESLIDGVRPLQPSALKSLHAEV
ERLTGLINDLYELALSDQGSLSYQRKECSLGALLSDFLEQSQTQLSEKDITLDFHSPNRP
LVLFADESRLIQLFRNLLINSLRYTDAGGQLRVRLFEDRNTGTATLIWEDSHPGVADKDL
EKLFDRLYRTDSARDRISGGAGLGLAICRAIAEGHQGWIEASHSELGGLKVAVHFPLYGK