Protein Info for B158DRAFT_0124 in Kangiella aquimarina DSM 16071

Annotation: NADH dehydrogenase subunit D (EC 1.6.5.3)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01962: NADH dehydrogenase (quinone), D subunit
  • amino acids 6 to 417 (412 residues), 614 bits, E=4.9e-189
• PF00346: Complex1_49kDa
  • amino acids 120 to 417 (298 residues), 402.4 bits, E=3.8e-125

Best Hits

Swiss-Prot: 81% identical to NUOD_NITOC: NADH-quinone oxidoreductase subunit D (nuoD) from Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)

KEGG orthology group: K00333, NADH dehydrogenase I subunit D [EC: 1.6.5.3] (inferred from 95% identity to kko:Kkor_0292)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

• aerobic respiration III (alternative oxidase pathway) (3/3 steps found)
• aerobic respiration I (cytochrome c) (3/4 steps found)
• NADH to cytochrome bd oxidase electron transfer I (1/2 steps found)
• NADH to cytochrome bo oxidase electron transfer I (1/2 steps found)
• Fe(II) oxidation (3/6 steps found)
• NAD(P)/NADPH interconversion (2/6 steps found)

KEGG Metabolic Maps

• Oxidative phosphorylation

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Protein Sequence (417 amino acids)

>B158DRAFT_0124 NADH dehydrogenase subunit D (EC 1.6.5.3) (Kangiella aquimarina DSM 16071)
MAEIRNYTINFGPQHPAAHGVLRLILEMDGETVVRADPHVGLLHRATEKLAESKPYNQSI
GYMDRLDYVSMMCNEHSYVLAIEKLMGIKPPERAQYIRVMFSEITRILNHLMWLGAHALD
IGAMTVFLYAFRERETLMDCYEAVSGARMHATYFRPGGVYRDLPEEMPQYKVSPFTNERK
AEELNANRQGSLLDFIWDFTETFPDRIDEYEALLTENRIWKQRTVGIGVVSPERALQLGF
SGPMLRGSGIAWDLRKKQPYEVYDRMDFDIPIGKTGDCYDRYLVRMEEMRQSNQIIRQCV
QWLRENPGPVMLENHKVTPPDRETMKHDMESLIHHFKLFTEGYCVPEGEAYAAIEHPKGE
FGVYLVSDGANKPYRVKIRAAGFAHLSAMNEMASGHMLADVVAIIGTQDIVFGEIDR