Protein Info for B158DRAFT_0040 in Kangiella aquimarina DSM 16071

Annotation: diguanylate cyclase (GGDEF) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details transmembrane" amino acids 399 to 417 (19 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 425 to 590 (166 residues), 153.4 bits, see alignment E=2.3e-49 PF00990: GGDEF" amino acids 430 to 586 (157 residues), 155.2 bits, see alignment E=1.3e-49

Best Hits

KEGG orthology group: None (inferred from 74% identity to kko:Kkor_0371)

Predicted SEED Role

"GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (602 amino acids)

>B158DRAFT_0040 diguanylate cyclase (GGDEF) domain (Kangiella aquimarina DSM 16071)
MTPGKKKLKSRSITRSISKFSIILVGILGGLLKATEITYIEELKIANHLRTTNPQQFLEQ
IDYVAGLQLPDEENEALRNYLLGYAAALKGNSEQAIGYYHKVIASRAHNPLVIRTKLALA
NLQVLNKDYAAALELIKNVLASANDQEDSLRNHIYQVAAIVYNEVGQYELAEQTLSHLTQ
IDDTVAGLKDKCLLAAVKAQTWYELSKIDAQEADFLEYSYQNCSEKEPVYALSAKFYWLA
DMIRSGEYKEASEEINSQLKVVEELGYSYLTTGYYTLNALSLSALGDRSAAQLYANKAIE
TAEKNNRDTVTTWLLEAYYLNSQLLKERGQLDQALEFLEEYLVKINRYKNDQSSKQLAYQ
LVEHETESKQQKIEQLNQQNLLLKLEQDLAKKEAVNNRLVLALALVLLGTLAFWTYRIKR
NQIRLRKQSQTDQLTGLSSRHHFYETAKAILQRSEQEKQDVGFILFDMDYFKSINDKYGH
LVGDWVLQKTAEVVKTSCRQNDLAGRLGGEEFAIFLPACNLKKAQQLAEICRKAISQVDT
TETGYRFDISASFGVTSTQLSGYDLMELIADADKAMYSAKSKGRNQIVVVDSFVKEFEQL
IS