Protein Info for Atu8131 in Agrobacterium fabrum C58

Annotation: pH adaption potassium efflux system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 972 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 36 to 60 (25 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details amino acids 113 to 130 (18 residues), see Phobius details amino acids 136 to 155 (20 residues), see Phobius details amino acids 167 to 190 (24 residues), see Phobius details amino acids 210 to 233 (24 residues), see Phobius details amino acids 247 to 269 (23 residues), see Phobius details amino acids 275 to 296 (22 residues), see Phobius details amino acids 303 to 322 (20 residues), see Phobius details amino acids 327 to 351 (25 residues), see Phobius details amino acids 367 to 390 (24 residues), see Phobius details amino acids 415 to 436 (22 residues), see Phobius details amino acids 463 to 486 (24 residues), see Phobius details amino acids 508 to 531 (24 residues), see Phobius details amino acids 580 to 600 (21 residues), see Phobius details amino acids 612 to 630 (19 residues), see Phobius details amino acids 637 to 657 (21 residues), see Phobius details amino acids 663 to 684 (22 residues), see Phobius details amino acids 707 to 727 (21 residues), see Phobius details amino acids 763 to 781 (19 residues), see Phobius details amino acids 819 to 843 (25 residues), see Phobius details amino acids 850 to 870 (21 residues), see Phobius details amino acids 886 to 906 (21 residues), see Phobius details amino acids 929 to 952 (24 residues), see Phobius details TIGR00940: monovalent cation:proton antiporter" amino acids 32 to 782 (751 residues), 961.7 bits, see alignment E=1.7e-293 PF00662: Proton_antipo_N" amino acids 70 to 115 (46 residues), 41.4 bits, see alignment 2.8e-14 PF00361: Proton_antipo_M" amino acids 131 to 409 (279 residues), 217.6 bits, see alignment E=5.7e-68 PF13244: MbhD" amino acids 621 to 686 (66 residues), 71.9 bits, see alignment 9.9e-24 PF20501: MbhE" amino acids 701 to 798 (98 residues), 154.3 bits, see alignment E=1.9e-49 PF04039: MnhB" amino acids 824 to 945 (122 residues), 124.3 bits, see alignment E=8.9e-40

Best Hits

Swiss-Prot: 68% identical to PHAAB_RHIME: Probable K(+)/H(+) antiporter subunit A/B (phaAB) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K05559, multicomponent K+:H+ antiporter subunit A (inferred from 100% identity to atu:Atu8131)

Predicted SEED Role

"Na(+) H(+) antiporter subunit A; Na(+) H(+) antiporter subunit B"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8U5J7 at UniProt or InterPro

Protein Sequence (972 amino acids)

>Atu8131 pH adaption potassium efflux system protein (Agrobacterium fabrum C58)
MTLATLLPFIVALPFVGAFLTAFMPRDGAAAGPASVAGGVALFGLVSSMFLYSTISGGGV
LKYDVEWLPQLGLNFTLRLDGFAWIFAILITGIGLLVVLYARYYMSSKDPIPRFFAFFLA
FMGSMLGVVLSGNVILLSIFWEMTSIFSFLLIGYWHQNAGARDGARMALTVTGIGGFSLL
AGLLILGHMAGSYDLDKIIEAGAAIRAHSLYLPALILILGGALTKSAQFPFHFWLPNAMA
APTPVSAYLHSATMVKAGVFLLARFWPVLAGTPEWFWLVGVAGVITLLLGAYFAMFQQDL
KGLLAYSTISHLGLITTLLSLGSPLAAVAAIFHMVNHATFKASLFMAAGIIDHETGTRDM
RRLSGLYTYMPATATLAMAASAAMAGVPLFNGFLSKEMFFAEAVETHADSLLDRALPYVA
TLSGAFAVAYSLRFIHTVFFGPKPVDLPNPNPHEPPRWMRFPIEFLVFACLIVGIVPSLS
IGPFLHSAVLSVLGAQTPVYSLSIWHGFNLPLIMSIAALIGGVTIYALLGGYFSRCDDGP
PIFRHLRGQRIFERILVTVSWKWARWLESTLGTRRLQPQLRLLILVALLAGFSPLFLSEF
SLSLPRVTTFDPIFAILWLIGMIAAMGAAWQAKYHRLAALIMLGVSGLVTCLTFVWLSAP
DLAITQLLVEIVTTVLILLGLRWLPKRFEKVDSSDELPAQLRRARDFLLAAASGIGMSVI
AYAVMTLPVPNAIATYFLERAYTEGGGTNVVNVILVDFRGFDTFGEIAVLAIVALTVFAL
LRRFRPAHESIGVPEQQQMQNAFDAERPDRSKGDTVRDYLYVPSIVMQWMFPVIVTFSIF
LFIRGHDMPGGGFAAGITMAIAFLLQYLAGGARWAEDRIRILPLRWMGFGLLMAAATGIG
SWYFGYPFLTTYFQYTDIPYIGKMPTASALLFDLGVFATVVGSTVLILIALAHQSLRNYR
VRTPEAAKAEDV