Protein Info for Atu6167 in Agrobacterium fabrum C58

Annotation: component of type IV secretion system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 245 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01464: SLT" amino acids 33 to 172 (140 residues), 72.9 bits, see alignment E=8.1e-25

Best Hits

Swiss-Prot: 100% identical to VIRB1_AGRFC: Protein virB1 (virB1) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03194, type IV secretion system protein VirB1 (inferred from 100% identity to atu:Atu6167)

Predicted SEED Role

"Peptidoglycan hydrolase VirB1, involved in T-DNA transfer"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P17791 at UniProt or InterPro

Protein Sequence (245 amino acids)

>Atu6167 component of type IV secretion system (Agrobacterium fabrum C58)
MLKATGPLSIILLASTCPSSGAAPLSFAEFNNFARECAPSVAPSTLAAIAQVESRFDPLA
VHDNTTGETLHWQNQAQATQVVMDRLEARHSLDVGLMQINSRNFSVLGLTPDGALQPCTS
LSVAANLLGSRYAGGNTADDEQLSLRRAISAYNTGDFTHGFANGYVRKVETAAQQLVPPL
TARPKDDREKPGSEETWDVWGAYKRRSPEGGAGGSSGPPPPPDEDNRKSEDDDQLLFDLN
QGGPQ