Protein Info for Atu6127 in Agrobacterium fabrum C58

Annotation: OriT nicking enzyme, Dtr system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 TIGR02768: Ti-type conjugative transfer relaxase TraA" amino acids 1 to 781 (781 residues), 1108.9 bits, see alignment E=0 PF03389: MobA_MobL" amino acids 17 to 243 (227 residues), 269 bits, see alignment E=8.4e-84 PF13604: AAA_30" amino acids 382 to 565 (184 residues), 190.9 bits, see alignment E=5.1e-60 PF13245: AAA_19" amino acids 386 to 510 (125 residues), 45 bits, see alignment E=3.1e-15 PF01443: Viral_helicase1" amino acids 692 to 736 (45 residues), 23 bits, see alignment (E = 1.6e-08) PF17841: Bep_C_terminal" amino acids 855 to 951 (97 residues), 138.9 bits, see alignment E=1.4e-44

Best Hits

Swiss-Prot: 100% identical to TRAA_AGRFC: Conjugal transfer protein TraA (traA) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: None (inferred from 100% identity to atu:Atu6127)

Predicted SEED Role

"Conjugal transfer protein TraA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q44349 at UniProt or InterPro

Protein Sequence (1100 amino acids)

>Atu6127 OriT nicking enzyme, Dtr system (Agrobacterium fabrum C58)
MAIAHFSASIVSRGDGRSVVLSAAYQHCAKMEYEREARTIDYTRKQGLVHQEFILPADAP
KWVRALIADCSVAGASEAFWNKVEAFEKRSDAQLARDLTIALPRELTSEQNIALVRDFVE
KHILGKGMVADWVYHDNPGNPHIHLMTTLRPLTEDGFGAKKVAVIGEDGQLVRTKSGKIL
YELWAGSTDDFNVVRDGWFERLNHHLTLGGIDLKIDGRSYEKQGIDLEPTIHLGVGAKAI
SRKAEQQGVRPELERIELNEERRSENTRRILKNPAIVLDLIMREKSVFDERDVAKVLHRY
VDDPAVFQQLMLRIILNPEVLRLQRDTIEFATGEKVPARYSTRAMIRLEATMARQAMWLS
DKETHAVSTAVLAATFGRHGRLSEEQKAAIECIAGPARIAAVVGRAGAGKTTMMKAAREA
WELAGYRVVGGALAGKASEGLDKEAGIESRTLSSWELRWNRGRDVLDNKTVFVMDEAGMV
ASKQMAGFVDAVVRAGAKIVLVGDPEQLQPIEAGAAFRAIVDRIGYAELETIYRQREDWM
RKASLDLARGNVEKALALYNANARIVGERLKAEAVERLIADWNRDYDQTKTTLILAHLRR
DVRMLNVMAREKLVERGIVGEGHVFRTADGERRFHAGDQIVFLKNETLLGVKNGMIGHVV
EAVPNRIVAVVGDRDHRRHVVVEQRFYSNLDHGYATTIHKSQGATVDRVKVLASLSLDRH
LTYVAMTRHREDLQLYYGCRSFAFNGGLAKVLSRKNAKETTLDYERGKLYREALRFAENR
GLHIMQVARTMLRDRLDWTLRQKTKVSDLVHRLRALGERLGLDQSPKTQTMKEAAPMVTG
IKTFSGSVADTVGDKLGADPTLKQQWEEVSARFRYVFADPETAFRAVNFDTVLADKEAAK
AVLQKLEAEPASIGALKGKTGILASKTEREARRVAEVNVPALKRDLEQYLRMRETATLRI
VTEEQALRQRVSIDIPALSPAARVVLERVRDAIDRNDLPAALGYALSNRETKLEIDGFNQ
AVTERFGERTLLSNVAREPSGKLYEKLSDGMRPEQKEQLKQAWPIMRTAQQLAAHERTVQ
SLKQAEELRQTLRQAPVLKQ