Protein Info for Atu5462 in Agrobacterium fabrum C58

Annotation: ABC transporter nucleotide binding/ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 115.5 bits, see alignment E=3e-37 PF17912: OB_MalK" amino acids 235 to 279 (45 residues), 36.2 bits, see alignment 9.6e-13

Best Hits

Swiss-Prot: 60% identical to UGPC_RUEST: sn-glycerol-3-phosphate import ATP-binding protein UgpC (ugpC) from Ruegeria sp. (strain TM1040)

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 100% identity to atu:Atu5462)

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, ATP-binding protein UgpC (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CL59 at UniProt or InterPro

Protein Sequence (360 amino acids)

>Atu5462 ABC transporter nucleotide binding/ATPase (Agrobacterium fabrum C58)
MANISIRNVSKSYGALNVLRPFSLEIENGEFVVLVGPSGCGKSTMLKILAGLEPASEGQI
FIGDNEVTDLAPGDRDIAMVFQNYALYPHLTVRQNIGFGLKMRGTDKAEIDRRVDDAARI
LEVTPYLDRKPKDLSGGQRQRVALGRAIVRQPQAFLMDEPLSNLDAKLRVHMRAEIGALH
KRIGVTTVYVTHDQVEAMTMADRVVIMQGGIIQQIAAPDELFNNPANLFVAGFIGSPGMN
FLNAELRGGAVTLFGQPVSLPGAVGREGSVIVGLRPEHLVLGDAPVTFDVRPTLVESLGS
EKYVYFDAEGARVADGEEGKSKGLIARVSHTGNLPGNEALRLGFDPAQLYLFDAKTGARL